Hosmane RS - Search Results

1

A novel, broad-spectrum anticancer compound containing the imidazo[4,5-e][1,3]diazepine ring system.

Xie M, Ujjinamatada RK, Sadowska M, Lapidus RG, Edelman MJ, Hosmane RS. Xie M, et al. Among authors: hosmane rs. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4386-9. doi: 10.1016/j.bmcl.2010.06.061. Epub 2010 Jun 15. Bioorg Med Chem Lett. 2010. PMID: 20594843 Free PMC article.

2

Nucleosides with self-complementary hydrogen-bonding motifs: synthesis and base-pairing studies of two nucleosides containing the imidazo[4,5-d]pyridazine ring system.

Ujjinamatada RK, Paulman RL, Ptak RG, Hosmane RS. Ujjinamatada RK, et al. Among authors: hosmane rs. Bioorg Med Chem. 2006 Sep 15;14(18):6359-67. doi: 10.1016/j.bmc.2006.05.043. Epub 2006 Jun 9. Bioorg Med Chem. 2006. PMID: 16765050

3

Design of inhibitors against guanase: synthesis and biochemical evaluation of analogues of azepinomycin.

Ujjinamatada RK, Bhan A, Hosmane RS. Ujjinamatada RK, et al. Among authors: hosmane rs. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5551-4. doi: 10.1016/j.bmcl.2006.08.033. Epub 2006 Aug 22. Bioorg Med Chem Lett. 2006. PMID: 16920357

4

An analogue of AICAR with dual inhibitory activity against WNV and HCV NTPase/helicase: synthesis and in vitro screening of 4-carbamoyl-5-(4,6-diamino-2,5-dihydro-1,3,5-triazin-2-yl)imidazole-1-beta-D-ribofuranoside.

Ujjinamatada RK, Baier A, Borowski P, Hosmane RS. Ujjinamatada RK, et al. Among authors: hosmane rs. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2285-8. doi: 10.1016/j.bmcl.2007.01.074. Epub 2007 Jan 27. Bioorg Med Chem Lett. 2007. PMID: 17289387 Free PMC article.

5

Inhibition of adenosine deaminase by analogues of adenosine and inosine, incorporating a common heterocyclic base, 4(7)-amino-6(5)H-imidazo[4,5-d]pyridazin-7(4)one.

Ujjinamatada RK, Phatak P, Burger AM, Hosmane RS. Ujjinamatada RK, et al. Among authors: hosmane rs. J Med Chem. 2008 Feb 14;51(3):694-8. doi: 10.1021/jm700931t. Epub 2008 Jan 4. J Med Chem. 2008. PMID: 18173230

6

The first synthesis of a novel 5:7:5-fused diimidazodiazepine ring system and some of its chemical properties.

Kumar R, Ujjinamatada RK, Hosmane RS. Kumar R, et al. Among authors: hosmane rs. Org Lett. 2008 Oct 16;10(20):4681-4. doi: 10.1021/ol8020176. Epub 2008 Sep 25. Org Lett. 2008. PMID: 18816128 Free PMC article.

7

Novel, Broad Spectrum Anti-Cancer Agents Containing the Tricyclic 5:7:5-Fused Diimidazodiazepine Ring System.

Kondaskar A, Kondaskar S, Kumar R, Fishbein JC, Muvarak N, Lapidus RG, Sadowska M, Edelman MJ, Bol GM, Vesuna F, Raman V, Hosmane RS. Kondaskar A, et al. Among authors: hosmane rs. ACS Med Chem Lett. 2010 Dec 31;2(3):252-256. doi: 10.1021/ml100281b. ACS Med Chem Lett. 2010. PMID: 21572541 Free PMC article.

8

Structure-based drug design and potent anti-cancer activity of tricyclic 5:7:5-fused diimidazo[4,5-d:4',5'-f][1,3]diazepines.

Kondaskar A, Kondaskar S, Fishbein JC, Carter-Cooper BA, Lapidus RG, Sadowska M, Edelman MJ, Hosmane RS. Kondaskar A, et al. Among authors: hosmane rs. Bioorg Med Chem. 2013 Feb 1;21(3):618-31. doi: 10.1016/j.bmc.2012.11.050. Epub 2012 Dec 11. Bioorg Med Chem. 2013. PMID: 23290252 Free PMC article.

9

Synthesis, anticancer activity, and SAR analyses of compounds containing the 5:7-fused 4,6,8-triaminoimidazo[4,5-e][1,3]diazepine ring system.

Xie M, Lapidus RG, Sadowska M, Edelman MJ, Hosmane RS. Xie M, et al. Among authors: hosmane rs. Bioorg Med Chem. 2016 Jun 15;24(12):2595-602. doi: 10.1016/j.bmc.2016.03.015. Epub 2016 Mar 9. Bioorg Med Chem. 2016. PMID: 27134120

10

A novel imidazole nucleoside containing a diaminodihydro-S-triazine as a substituent: inhibitory activity against the West Nile virus NTPase/helicase.

Ujjinamatada RK, Agasimundin YS, Zhang P, Hosmane RS, Schuessler R, Borowski P, Kalicharran K, Fattom A. Ujjinamatada RK, et al. Among authors: hosmane rs. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1775-88. doi: 10.1080/15257770500267063. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438047

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