Hosaka T - Search Results

1

Prediction Model of Aryl Hydrocarbon Receptor Activation by a Novel QSAR Approach, DeepSnap-Deep Learning.

Matsuzaka Y, Hosaka T, Ogaito A, Yoshinari K, Uesawa Y. Matsuzaka Y, et al. Among authors: hosaka t. Molecules. 2020 Mar 13;25(6):1317. doi: 10.3390/molecules25061317. Molecules. 2020. PMID: 32183141 Free PMC article.

2

Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid.

Abe T, Takahashi M, Kano M, Amaike Y, Ishii C, Maeda K, Kudoh Y, Morishita T, Hosaka T, Sasaki T, Kodama S, Matsuzawa A, Kojima H, Yoshinari K. Abe T, et al. Among authors: hosaka t. Arch Toxicol. 2017 Jun;91(6):2365-2374. doi: 10.1007/s00204-016-1888-3. Epub 2016 Nov 10. Arch Toxicol. 2017. PMID: 27832320

3

[Construction of the Database of Rat Repeated-dose Toxicity Tests of Pesticides for the Toxicological Characterization of Hepatocyte Hypertrophy].

Masuda A, Masuda M, Kawano T, Kitsunai Y, Nakayama H, Nakajima H, Kojima H, Kitamura S, Uramaru N, Hosaka T, Sasaki T, Yoshinari K. Masuda A, et al. Among authors: hosaka t. Yakugaku Zasshi. 2017;137(5):611-622. doi: 10.1248/yakushi.16-00259. Yakugaku Zasshi. 2017. PMID: 28458293 Free article. Japanese.

4

Characterization of CYP2C Induction in Cryopreserved Human Hepatocytes and Its Application in the Prediction of the Clinical Consequences of the Induction.

Nagai M, Hosaka T, Satsukawa M, Yoshinari K. Nagai M, et al. Among authors: hosaka t. J Pharm Sci. 2018 Sep;107(9):2479-2488. doi: 10.1016/j.xphs.2018.05.008. Epub 2018 May 23. J Pharm Sci. 2018. PMID: 29802934

5

Role of YAP Activation in Nuclear Receptor CAR-Mediated Proliferation of Mouse Hepatocytes.

Abe T, Amaike Y, Shizu R, Takahashi M, Kano M, Hosaka T, Sasaki T, Kodama S, Matsuzawa A, Yoshinari K. Abe T, et al. Among authors: hosaka t. Toxicol Sci. 2018 Oct 1;165(2):408-419. doi: 10.1093/toxsci/kfy149. Toxicol Sci. 2018. PMID: 29893953

6

Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR.

Yoshimaru S, Shizu R, Tsuruta S, Amaike Y, Kano M, Hosaka T, Sasaki T, Yoshinari K. Yoshimaru S, et al. Among authors: hosaka t. J Toxicol Sci. 2018;43(7):443-450. doi: 10.2131/jts.43.443. J Toxicol Sci. 2018. PMID: 29973476 Free article.

7

Possible involvement of the competition for the transcriptional coactivator glucocorticoid receptor-interacting protein 1 in the inflammatory signal-dependent suppression of PXR-mediated CYP3A induction in vitro.

Okamura M, Shizu R, Hosaka T, Sasaki T, Yoshinari K. Okamura M, et al. Among authors: hosaka t. Drug Metab Pharmacokinet. 2019 Aug;34(4):272-279. doi: 10.1016/j.dmpk.2019.04.005. Epub 2019 Apr 19. Drug Metab Pharmacokinet. 2019. PMID: 31280915

8

Functional Interaction between Pregnane X Receptor and Yes-Associated Protein in Xenobiotic-Dependent Liver Hypertrophy and Drug Metabolism.

Abe T, Shizu R, Sasaki T, Shimizu Y, Hosaka T, Kodama S, Matsuzawa A, Yoshinari K. Abe T, et al. Among authors: hosaka t. J Pharmacol Exp Ther. 2019 Dec;371(3):590-601. doi: 10.1124/jpet.119.258632. Epub 2019 Sep 18. J Pharmacol Exp Ther. 2019. PMID: 31533970

9

Application of cytochrome P450 reactivity on the characterization of chemical compounds and its association with repeated-dose toxicity.

Watanabe M, Sasaki T, Takeshita JI, Kushida M, Shimizu Y, Oki H, Kitsunai Y, Nakayama H, Saruhashi H, Ogura R, Shizu R, Hosaka T, Yoshinari K. Watanabe M, et al. Among authors: hosaka t. Toxicol Appl Pharmacol. 2020 Feb 1;388:114854. doi: 10.1016/j.taap.2019.114854. Epub 2019 Dec 10. Toxicol Appl Pharmacol. 2020. PMID: 31836524

10

Antiepileptic Drug-Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator-Activated Receptor α and Peroxisome Proliferator-Activated Receptor γ Coactivator 1α-Dependent Gene Expression to Increase Blood Triglyceride Levels.

Shizu R, Otsuka Y, Ezaki K, Ishii C, Arakawa S, Amaike Y, Abe T, Hosaka T, Sasaki T, Kanno Y, Miyata M, Yamazoe Y, Yoshinari K. Shizu R, et al. Among authors: hosaka t. Mol Pharmacol. 2020 Nov;98(5):634-647. doi: 10.1124/molpharm.120.000103. Epub 2020 Sep 5. Mol Pharmacol. 2020. PMID: 32892155

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