Horton JR - Search Results

1

HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription.

Huang P, Peslak SA, Ren R, Khandros E, Qin K, Keller CA, Giardine B, Bell HW, Lan X, Sharma M, Horton JR, Abdulmalik O, Chou ST, Shi J, Crossley M, Hardison RC, Cheng X, Blobel GA. Huang P, et al. Among authors: horton jr. Nat Genet. 2022 Sep;54(9):1417-1426. doi: 10.1038/s41588-022-01152-6. Epub 2022 Aug 8. Nat Genet. 2022. PMID: 35941187 Free PMC article.

2

PvuII endonuclease contains two calcium ions in active sites.

Horton JR, Cheng X. Horton JR, et al. J Mol Biol. 2000 Jul 28;300(5):1049-56. doi: 10.1006/jmbi.2000.3938. J Mol Biol. 2000. PMID: 10903853

3

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.

Lan F, Collins RE, De Cegli R, Alpatov R, Horton JR, Shi X, Gozani O, Cheng X, Shi Y. Lan F, et al. Among authors: horton jr. Nature. 2007 Aug 9;448(7154):718-22. doi: 10.1038/nature06034. Nature. 2007. PMID: 17687328 Free PMC article.

4

The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules.

Collins RE, Northrop JP, Horton JR, Lee DY, Zhang X, Stallcup MR, Cheng X. Collins RE, et al. Among authors: horton jr. Nat Struct Mol Biol. 2008 Mar;15(3):245-50. doi: 10.1038/nsmb.1384. Epub 2008 Feb 10. Nat Struct Mol Biol. 2008. PMID: 18264113 Free PMC article.

5

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix.

Hashimoto H, Horton JR, Zhang X, Bostick M, Jacobsen SE, Cheng X. Hashimoto H, et al. Among authors: horton jr. Nature. 2008 Oct 9;455(7214):826-9. doi: 10.1038/nature07280. Epub 2008 Sep 3. Nature. 2008. PMID: 18772888 Free PMC article.

6

UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications.

Hashimoto H, Horton JR, Zhang X, Cheng X. Hashimoto H, et al. Among authors: horton jr. Epigenetics. 2009 Jan;4(1):8-14. doi: 10.4161/epi.4.1.7370. Epub 2009 Jan 10. Epigenetics. 2009. PMID: 19077538 Free PMC article.

7

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.

Horton JR, Upadhyay AK, Qi HH, Zhang X, Shi Y, Cheng X. Horton JR, et al. Nat Struct Mol Biol. 2010 Jan;17(1):38-43. doi: 10.1038/nsmb.1753. Epub 2009 Dec 20. Nat Struct Mol Biol. 2010. PMID: 20023638 Free PMC article.

8

Coordinated methyl-lysine erasure: structural and functional linkage of a Jumonji demethylase domain and a reader domain.

Upadhyay AK, Horton JR, Zhang X, Cheng X. Upadhyay AK, et al. Among authors: horton jr. Curr Opin Struct Biol. 2011 Dec;21(6):750-60. doi: 10.1016/j.sbi.2011.08.003. Epub 2011 Aug 25. Curr Opin Struct Biol. 2011. PMID: 21872465 Free PMC article.

9

Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.

Horton JR, Zhang X, Blumenthal RM, Cheng X. Horton JR, et al. Nucleic Acids Res. 2015 Apr 30;43(8):4296-308. doi: 10.1093/nar/gkv251. Epub 2015 Apr 6. Nucleic Acids Res. 2015. PMID: 25845600 Free PMC article.

10

Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta.

Hong S, Wang D, Horton JR, Zhang X, Speck SH, Blumenthal RM, Cheng X. Hong S, et al. Among authors: horton jr. Nucleic Acids Res. 2017 Mar 17;45(5):2503-2515. doi: 10.1093/nar/gkx057. Nucleic Acids Res. 2017. PMID: 28158710 Free PMC article.

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