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P. aeruginosa Infected 3D Co-Culture of Bronchial Epithelial Cells and Macrophages at Air-Liquid Interface for Preclinical Evaluation of Anti-Infectives.
J Vis Exp. 2020 Jun 15;(160). doi: 10.3791/61069.
J Vis Exp. 2020.
PMID: 32597860
Transferring Microclusters of P. aeruginosa Biofilms to the Air-Liquid Interface of Bronchial Epithelial Cells for Repeated Deposition of Aerosolized Tobramycin.
Horstmann JC, Laric A, Boese A, Yildiz D, Röhrig T, Empting M, Frank N, Krug D, Müller R, Schneider-Daum N, de Souza Carvalho-Wodarz C, Lehr CM.
Horstmann JC, et al.
ACS Infect Dis. 2022 Jan 14;8(1):137-149. doi: 10.1021/acsinfecdis.1c00444. Epub 2021 Dec 17.
ACS Infect Dis. 2022.
PMID: 34919390
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Disease Models: Lung Models for Testing Drugs Against Inflammation and Infection.
Carius P, Horstmann JC, de Souza Carvalho-Wodarz C, Lehr CM.
Carius P, et al. Among authors: horstmann jc.
Handb Exp Pharmacol. 2021;265:157-186. doi: 10.1007/164_2020_366.
Handb Exp Pharmacol. 2021.
PMID: 33095300
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A pulmonary mucus surrogate for investigating antibiotic permeation and activity against Pseudomonas aeruginosa biofilms.
Frisch S, Boese A, Huck B, Horstmann JC, Ho DK, Schwarzkopf K, Murgia X, Loretz B, de Souza Carvalho-Wodarz C, Lehr CM.
Frisch S, et al. Among authors: horstmann jc.
J Antimicrob Chemother. 2021 May 12;76(6):1472-1479. doi: 10.1093/jac/dkab068.
J Antimicrob Chemother. 2021.
PMID: 33712824
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Tobramycin Liquid Crystal Nanoparticles Eradicate Cystic Fibrosis-Related Pseudomonas aeruginosa Biofilms.
Thorn CR, Carvalho-Wodarz CS, Horstmann JC, Lehr CM, Prestidge CA, Thomas N.
Thorn CR, et al. Among authors: horstmann jc.
Small. 2021 Jun;17(24):e2100531. doi: 10.1002/smll.202100531. Epub 2021 May 12.
Small. 2021.
PMID: 33978317
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A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms.
Schütz C, Ho DK, Hamed MM, Abdelsamie AS, Röhrig T, Herr C, Kany AM, Rox K, Schmelz S, Siebenbürger L, Wirth M, Börger C, Yahiaoui S, Bals R, Scrima A, Blankenfeldt W, Horstmann JC, Christmann R, Murgia X, Koch M, Berwanger A, Loretz B, Hirsch AKH, Hartmann RW, Lehr CM, Empting M.
Schütz C, et al. Among authors: horstmann jc.
Adv Sci (Weinh). 2021 Jun;8(12):e2004369. doi: 10.1002/advs.202004369. Epub 2021 Mar 18.
Adv Sci (Weinh). 2021.
PMID: 34165899
Free PMC article.
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A Custom-Made Device for Reproducibly Depositing Pre-metered Doses of Nebulized Drugs on Pulmonary Cells in vitro.
Horstmann JC, Thorn CR, Carius P, Graef F, Murgia X, de Souza Carvalho-Wodarz C, Lehr CM.
Horstmann JC, et al.
Front Bioeng Biotechnol. 2021 Apr 21;9:643491. doi: 10.3389/fbioe.2021.643491. eCollection 2021.
Front Bioeng Biotechnol. 2021.
PMID: 33968912
Free PMC article.
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