Horsfall L - Search Results

1

Mercaptophosphonate compounds as broad-spectrum inhibitors of the metallo-beta-lactamases.

Lassaux P, Hamel M, Gulea M, Delbrück H, Mercuri PS, Horsfall L, Dehareng D, Kupper M, Frère JM, Hoffmann K, Galleni M, Bebrone C. Lassaux P, et al. Among authors: horsfall l. J Med Chem. 2010 Jul 8;53(13):4862-76. doi: 10.1021/jm100213c. J Med Chem. 2010. PMID: 20527888

2

Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols.

Liénard BM, Garau G, Horsfall L, Karsisiotis AI, Damblon C, Lassaux P, Papamicael C, Roberts GC, Galleni M, Dideberg O, Frère JM, Schofield CJ. Liénard BM, et al. Among authors: horsfall l. Org Biomol Chem. 2008 Jul 7;6(13):2282-94. doi: 10.1039/b802311e. Epub 2008 May 7. Org Biomol Chem. 2008. PMID: 18563261

3

Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila.

Horsfall LE, Garau G, Liénard BM, Dideberg O, Schofield CJ, Frère JM, Galleni M. Horsfall LE, et al. Antimicrob Agents Chemother. 2007 Jun;51(6):2136-42. doi: 10.1128/AAC.00866-06. Epub 2007 Feb 16. Antimicrob Agents Chemother. 2007. PMID: 17307979 Free PMC article.

4

Inhibitors of the FEZ-1 metallo-beta-lactamase.

Liénard BM, Horsfall LE, Galleni M, Frère JM, Schofield CJ. Liénard BM, et al. Bioorg Med Chem Lett. 2007 Feb 15;17(4):964-8. doi: 10.1016/j.bmcl.2006.11.053. Epub 2006 Nov 18. Bioorg Med Chem Lett. 2007. PMID: 17157014

5

Broad antibiotic resistance profile of the subclass B3 metallo-β-lactamase GOB-1, a di-zinc enzyme.

Horsfall LE, Izougarhane Y, Lassaux P, Selevsek N, Liénard BM, Poirel L, Kupper MB, Hoffmann KM, Frère JM, Galleni M, Bebrone C. Horsfall LE, et al. FEBS J. 2011 Apr;278(8):1252-63. doi: 10.1111/j.1742-4658.2011.08046.x. Epub 2011 Mar 4. FEBS J. 2011. PMID: 21299838 Free article.

6

Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803.

McNeill LA, Hewitson KS, Claridge TD, Seibel JF, Horsfall LE, Schofield CJ. McNeill LA, et al. Biochem J. 2002 Nov 1;367(Pt 3):571-5. doi: 10.1042/BJ20021162. Biochem J. 2002. PMID: 12215170 Free PMC article.

7

The use of dioxygen by HIF prolyl hydroxylase (PHD1).

McNeill LA, Hewitson KS, Gleadle JM, Horsfall LE, Oldham NJ, Maxwell PH, Pugh CW, Ratcliffe PJ, Schofield CJ. McNeill LA, et al. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1547-50. doi: 10.1016/s0960-894x(02)00219-6. Bioorg Med Chem Lett. 2002. PMID: 12039559

8

Identification and characterization of important residues in the catalytic mechanism of CMP-Neu5Ac synthetase from Neisseria meningitidis.

Horsfall LE, Nelson A, Berry A. Horsfall LE, et al. FEBS J. 2010 Jul;277(13):2779-90. doi: 10.1111/j.1742-4658.2010.07696.x. Epub 2010 May 20. FEBS J. 2010. PMID: 20491913 Free PMC article.

9

Synthetic biology approaches towards the recycling of metals from the environment.

Capeness MJ, Horsfall LE. Capeness MJ, et al. Biochem Soc Trans. 2020 Aug 28;48(4):1367-1378. doi: 10.1042/BST20190837. Biochem Soc Trans. 2020. PMID: 32627824 Free PMC article. Review.

10

Exploring the potential of metallic nanoparticles within synthetic biology.

Edmundson MC, Capeness M, Horsfall L. Edmundson MC, et al. Among authors: horsfall l. N Biotechnol. 2014 Dec 25;31(6):572-8. doi: 10.1016/j.nbt.2014.03.004. Epub 2014 Mar 26. N Biotechnol. 2014. PMID: 24681407 Free article.

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