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Inhibiting CSF1R alleviates cerebrovascular white matter disease and cognitive impairment.
Askew KE, Beverley J, Sigfridsson E, Szymkowiak S, Emelianova K, Dando O, Hardingham GE, Duncombe J, Hennessy E, Koudelka J, Samarasekera N, Salman RA, Smith C, Tavares AAS, Gomez-Nicola D, Kalaria RN, McColl BW, Horsburgh K. Askew KE, et al. Among authors: horsburgh k. Glia. 2024 Feb;72(2):375-395. doi: 10.1002/glia.24481. Epub 2023 Nov 1. Glia. 2024. PMID: 37909242 Free PMC article.
Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia.
Duncombe J, Kitamura A, Hase Y, Ihara M, Kalaria RN, Horsburgh K. Duncombe J, et al. Among authors: horsburgh k. Clin Sci (Lond). 2017 Sep 28;131(19):2451-2468. doi: 10.1042/CS20160727. Print 2017 Oct 1. Clin Sci (Lond). 2017. PMID: 28963120 Free article. Review.
Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.
Horsburgh K, Wardlaw JM, van Agtmael T, Allan SM, Ashford MLJ, Bath PM, Brown R, Berwick J, Cader MZ, Carare RO, Davis JB, Duncombe J, Farr TD, Fowler JH, Goense J, Granata A, Hall CN, Hainsworth AH, Harvey A, Hawkes CA, Joutel A, Kalaria RN, Kehoe PG, Lawrence CB, Lockhart A, Love S, Macleod MR, Macrae IM, Markus HS, McCabe C, McColl BW, Meakin PJ, Miller A, Nedergaard M, O'Sullivan M, Quinn TJ, Rajani R, Saksida LM, Smith C, Smith KJ, Touyz RM, Trueman RC, Wang T, Williams A, Williams SCR, Work LM. Horsburgh K, et al. Clin Sci (Lond). 2018 Apr 30;132(8):851-868. doi: 10.1042/CS20171620. Print 2018 Apr 30. Clin Sci (Lond). 2018. PMID: 29712883 Free PMC article.
104 results