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The 5:2 diet does not increase adult hippocampal neurogenesis or enhance spatial memory in mice.
EMBO Rep. 2023 Dec 6;24(12):e57269. doi: 10.15252/embr.202357269. Epub 2023 Nov 21.
EMBO Rep. 2023.
PMID: 37987211
Free PMC article.
Short-term calorie restriction enhances adult hippocampal neurogenesis and remote fear memory in a Ghsr-dependent manner.
Hornsby AK, Redhead YT, Rees DJ, Ratcliff MS, Reichenbach A, Wells T, Francis L, Amstalden K, Andrews ZB, Davies JS.
Hornsby AK, et al.
Psychoneuroendocrinology. 2016 Jan;63:198-207. doi: 10.1016/j.psyneuen.2015.09.023. Epub 2015 Sep 25.
Psychoneuroendocrinology. 2016.
PMID: 26460782
Free PMC article.
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Calorie restriction activates new adult born olfactory-bulb neurones in a ghrelin-dependent manner but acyl-ghrelin does not enhance subventricular zone neurogenesis.
Ratcliff M, Rees D, McGrady S, Buntwal L, Hornsby AKE, Bayliss J, Kent BA, Bussey T, Saksida L, Beynon AL, Howell OW, Morgan AH, Sun Y, Andrews ZB, Wells T, Davies JS.
Ratcliff M, et al. Among authors: hornsby ake.
J Neuroendocrinol. 2019 Jul;31(7):e12755. doi: 10.1111/jne.12755. Epub 2019 Jun 24.
J Neuroendocrinol. 2019.
PMID: 31179562
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Unacylated-Ghrelin Impairs Hippocampal Neurogenesis and Memory in Mice and Is Altered in Parkinson's Dementia in Humans.
Hornsby AKE, Buntwal L, Carisi MC, Santos VV, Johnston F, Roberts LD, Sassi M, Mequinion M, Stark R, Reichenbach A, Lockie SH, Siervo M, Howell O, Morgan AH, Wells T, Andrews ZB, Burn DJ, Davies JS.
Hornsby AKE, et al.
Cell Rep Med. 2020 Oct 20;1(7):100120. doi: 10.1016/j.xcrm.2020.100120.
Cell Rep Med. 2020.
PMID: 33103129
Free PMC article.
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The orexigenic hormone acyl-ghrelin increases adult hippocampal neurogenesis and enhances pattern separation.
Kent BA, Beynon AL, Hornsby AK, Bekinschtein P, Bussey TJ, Davies JS, Saksida LM.
Kent BA, et al. Among authors: hornsby ak.
Psychoneuroendocrinology. 2015 Jan;51:431-9. doi: 10.1016/j.psyneuen.2014.10.015. Epub 2014 Oct 23.
Psychoneuroendocrinology. 2015.
PMID: 25462915
Free PMC article.
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