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106 results

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A Phase I/II Study of GSK525762 Combined with Fulvestrant in Patients with Hormone Receptor-positive/HER2-negative Advanced or Metastatic Breast Cancer.
Cescon DW, Hilton J, Morales Murilo S, Layman RM, Pluard T, Yeo B, Park IH, Provencher L, Kim SB, Im YH, Wyce A, Krishnatry AS, Hicks K, Zhang Q, Barbash O, Khaled A, Horner T, Dhar A, Oliveira M, Sparano JA. Cescon DW, et al. Among authors: horner t. Clin Cancer Res. 2024 Jan 17;30(2):334-343. doi: 10.1158/1078-0432.CCR-23-0133. Clin Cancer Res. 2024. PMID: 37992310 Free PMC article. Clinical Trial.
Zinc stimulation of coastal productivity in low carbon dioxide environments.
Kell RM, Subhas AV, Schanke NL, Lees LE, Chmiel RJ, Rao D, Brisbin MMM, Moran DM, McIlvin MR, Bolinesi F, Mangoni O, Casotti R, Balestra C, Horner T, Dunbar RB, Allen AE, DiTullio GR, Saito MA. Kell RM, et al. Among authors: horner t. bioRxiv [Preprint]. 2023 Nov 5:2023.11.05.565706. doi: 10.1101/2023.11.05.565706. bioRxiv. 2023. PMID: 37961643 Free PMC article. Preprint.
Paediatric Strategy Forum for medicinal product development of DNA damage response pathway inhibitors in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
Pearson ADJ, Federico S, Gatz SA, Ortiz M, Lesa G, Scobie N, Gounaris I, Weiner SL, Weigel B, Unger TJ, Stewart E, Smith M, Slotkin EK, Reaman G, Pappo A, Nysom K, Norga K, McDonough J, Marshall LV, Ludwinski D, Ligas F, Karres D, Kool M, Horner TJ, Henssen A, Heenen D, Hawkins DS, Gore L, Bender JG, Galluzzo S, Fox E, de Rojas T, Davies BR, Chakrabarti J, Carmichael J, Bradford D, Blanc P, Bernardi R, Benchetrit S, Akindele K, Vassal G. Pearson ADJ, et al. Among authors: horner tj. Eur J Cancer. 2023 Sep;190:112950. doi: 10.1016/j.ejca.2023.112950. Epub 2023 Jun 21. Eur J Cancer. 2023. PMID: 37441939 Free article. Review.
A Phase I/II Open-Label Study of Molibresib for the Treatment of Relapsed/Refractory Hematologic Malignancies.
Dawson MA, Borthakur G, Huntly BJP, Karadimitris A, Alegre A, Chaidos A, Vogl DT, Pollyea DA, Davies FE, Morgan GJ, Glass JL, Kamdar M, Mateos MV, Tovar N, Yeh P, Delgado RG, Basheer F, Marando L, Gallipoli P, Wyce A, Krishnatry AS, Barbash O, Bakirtzi E, Ferron-Brady G, Karpinich NO, McCabe MT, Foley SW, Horner T, Dhar A, Kremer BE, Dickinson M. Dawson MA, et al. Among authors: horner t. Clin Cancer Res. 2023 Feb 16;29(4):711-722. doi: 10.1158/1078-0432.CCR-22-1284. Clin Cancer Res. 2023. PMID: 36350312 Free PMC article. Clinical Trial.
Microbial functional diversity across biogeochemical provinces in the central Pacific Ocean.
Saunders JK, McIlvin MR, Dupont CL, Kaul D, Moran DM, Horner T, Laperriere SM, Webb EA, Bosak T, Santoro AE, Saito MA. Saunders JK, et al. Among authors: horner t. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2200014119. doi: 10.1073/pnas.2200014119. Epub 2022 Sep 6. Proc Natl Acad Sci U S A. 2022. PMID: 36067300 Free PMC article.
Strong Margin Influence on the Arctic Ocean Barium Cycle Revealed by Pan-Arctic Synthesis.
Whitmore LM, Shiller AM, Horner TJ, Xiang Y, Auro ME, Bauch D, Dehairs F, Lam PJ, Li J, Maldonado MT, Mears C, Newton R, Pasqualini A, Planquette H, Rember R, Thomas H. Whitmore LM, et al. Among authors: horner tj. J Geophys Res Oceans. 2022 Apr;127(4):e2021JC017417. doi: 10.1029/2021JC017417. Epub 2022 Mar 30. J Geophys Res Oceans. 2022. PMID: 35865799 Free PMC article.
Safety, pharmacokinetic, pharmacodynamic and clinical activity of molibresib for the treatment of nuclear protein in testis carcinoma and other cancers: Results of a Phase I/II open-label, dose escalation study.
Cousin S, Blay JY, Garcia IB, de Bono JS, Le Tourneau C, Moreno V, Trigo J, Hann CL, Azad AA, Im SA, Cassier PA, French CA, Italiano A, Keedy VL, Plummer R, Sablin MP, Hemming ML, Ferron-Brady G, Wyce A, Khaled A, Datta A, Foley SW, McCabe MT, Wu Y, Horner T, Kremer BE, Dhar A, O'Dwyer PJ, Shapiro GI, Piha-Paul SA. Cousin S, et al. Among authors: horner t. Int J Cancer. 2022 Mar 15;150(6):993-1006. doi: 10.1002/ijc.33861. Epub 2021 Nov 26. Int J Cancer. 2022. PMID: 34724226 Free article. Clinical Trial.
The Sedimentary Geochemistry and Paleoenvironments Project.
Farrell ÚC, Samawi R, Anjanappa S, Klykov R, Adeboye OO, Agic H, Ahm AC, Boag TH, Bowyer F, Brocks JJ, Brunoir TN, Canfield DE, Chen X, Cheng M, Clarkson MO, Cole DB, Cordie DR, Crockford PW, Cui H, Dahl TW, Mouro LD, Dewing K, Dornbos SQ, Drabon N, Dumoulin JA, Emmings JF, Endriga CR, Fraser TA, Gaines RR, Gaschnig RM, Gibson TM, Gilleaudeau GJ, Gill BC, Goldberg K, Guilbaud R, Halverson GP, Hammarlund EU, Hantsoo KG, Henderson MA, Hodgskiss MSW, Horner TJ, Husson JM, Johnson B, Kabanov P, Brenhin Keller C, Kimmig J, Kipp MA, Knoll AH, Kreitsmann T, Kunzmann M, Kurzweil F, LeRoy MA, Li C, Lipp AG, Loydell DK, Lu X, Macdonald FA, Magnall JM, Mänd K, Mehra A, Melchin MJ, Miller AJ, Mills NT, Mwinde CN, O'Connell B, Och LM, Ossa Ossa F, Pagès A, Paiste K, Partin CA, Peters SE, Petrov P, Playter TL, Plaza-Torres S, Porter SM, Poulton SW, Pruss SB, Richoz S, Ritzer SR, Rooney AD, Sahoo SK, Schoepfer SD, Sclafani JA, Shen Y, Shorttle O, Slotznick SP, Smith EF, Spinks S, Stockey RG, Strauss JV, Stüeken EE, Tecklenburg S, Thomson D, Tosca NJ, Uhlein GJ, Vizcaíno MN, Wang H, White T, Wilby PR, Woltz CR, Wood RA, Xiang L, Yurchenko IA, Zhang T, Planavsky NJ, Lau KV, Johnston DT, Spe… See abstract for full author list ➔ Farrell ÚC, et al. Among authors: horner tj. Geobiology. 2021 Nov;19(6):545-556. doi: 10.1111/gbi.12462. Epub 2021 Jul 5. Geobiology. 2021. PMID: 34219351 Free PMC article. No abstract available.
Groundwater discharge impacts marine isotope budgets of Li, Mg, Ca, Sr, and Ba.
Mayfield KK, Eisenhauer A, Santiago Ramos DP, Higgins JA, Horner TJ, Auro M, Magna T, Moosdorf N, Charette MA, Gonneea ME, Brady CE, Komar N, Peucker-Ehrenbrink B, Paytan A. Mayfield KK, et al. Among authors: horner tj. Nat Commun. 2021 Jan 8;12(1):148. doi: 10.1038/s41467-020-20248-3. Nat Commun. 2021. PMID: 33420047 Free PMC article.
Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors.
Piha-Paul SA, Hann CL, French CA, Cousin S, Braña I, Cassier PA, Moreno V, de Bono JS, Harward SD, Ferron-Brady G, Barbash O, Wyce A, Wu Y, Horner T, Annan M, Parr NJ, Prinjha RK, Carpenter CL, Hilton J, Hong DS, Haas NB, Markowski MC, Dhar A, O'Dwyer PJ, Shapiro GI. Piha-Paul SA, et al. Among authors: horner t. JNCI Cancer Spectr. 2019 Nov 6;4(2):pkz093. doi: 10.1093/jncics/pkz093. eCollection 2020 Apr. JNCI Cancer Spectr. 2019. PMID: 32328561 Free PMC article.
106 results