Hornebeck W - Search Results

1

Neutrophil elastase as a target in lung cancer.

Moroy G, Alix AJ, Sapi J, Hornebeck W, Bourguet E. Moroy G, et al. Among authors: hornebeck w. Anticancer Agents Med Chem. 2012 Jul;12(6):565-79. doi: 10.2174/187152012800617696. Anticancer Agents Med Chem. 2012. PMID: 22263788 Review.

2

Simultaneous presence of unsaturation and long alkyl chain at P'1 of Ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9) inhibition as shown by molecular modelling studies.

Moroy G, Denhez C, El Mourabit H, Toribio A, Dassonville A, Decarme M, Renault JH, Mirand C, Bellon G, Sapi J, Alix AJ, Hornebeck W, Bourguet E. Moroy G, et al. Among authors: hornebeck w. Bioorg Med Chem. 2007 Jul 15;15(14):4753-66. doi: 10.1016/j.bmc.2007.05.001. Epub 2007 May 6. Bioorg Med Chem. 2007. PMID: 17512742

3

Introduction of the 4-(4-bromophenyl)benzenesulfonyl group to hydrazide analogs of Ilomastat leads to potent gelatinase B (MMP-9) inhibitors with improved selectivity.

Ledour G, Moroy G, Rouffet M, Bourguet E, Guillaume D, Decarme M, Elmourabit H, Augé F, Alix AJ, Laronze JY, Bellon G, Hornebeck W, Sapi J. Ledour G, et al. Among authors: hornebeck w. Bioorg Med Chem. 2008 Sep 15;16(18):8745-59. doi: 10.1016/j.bmc.2008.07.041. Epub 2008 Jul 20. Bioorg Med Chem. 2008. PMID: 18782669

4

Control of melanoma invasiveness by anticollagenolytic agents: a reappraisal of an old concept.

Bourguet E, Sapi J, Emonard H, Hornebeck W. Bourguet E, et al. Among authors: hornebeck w. Anticancer Agents Med Chem. 2009 Jun;9(5):576-9. doi: 10.2174/187152009788451842. Anticancer Agents Med Chem. 2009. PMID: 19519299

5

Inhibition of human leukocyte elastase, plasmin and matrix metalloproteinases by oleic acid and oleoyl-galardin derivative(s).

Moroy G, Bourguet E, Decarme M, Sapi J, Alix AJ, Hornebeck W, Lorimier S. Moroy G, et al. Among authors: hornebeck w. Biochem Pharmacol. 2011 Mar 1;81(5):626-35. doi: 10.1016/j.bcp.2010.12.001. Epub 2010 Dec 10. Biochem Pharmacol. 2011. PMID: 21146503

6

Conformational dependence of collagenase (matrix metalloproteinase-1) up-regulation by elastin peptides in cultured fibroblasts.

Brassart B, Fuchs P, Huet E, Alix AJ, Wallach J, Tamburro AM, Delacoux F, Haye B, Emonard H, Hornebeck W, Debelle L. Brassart B, et al. Among authors: hornebeck w. J Biol Chem. 2001 Feb 16;276(7):5222-7. doi: 10.1074/jbc.M003642200. Epub 2000 Nov 17. J Biol Chem. 2001. PMID: 11084020 Free article.

7

Predictions of the secondary structure and antigenicity of human and bovine tropoelastins.

Debelle L, Wei SM, Jacob MP, Hornebeck W, Alix AJ. Debelle L, et al. Among authors: hornebeck w. Eur Biophys J. 1992;21(5):321-9. doi: 10.1007/BF00188344. Eur Biophys J. 1992. PMID: 1282881

8

Improved gelatinase a selectivity by novel zinc binding groups containing galardin derivatives.

Augé F, Hornebeck W, Decarme M, Laronze JY. Augé F, et al. Among authors: hornebeck w. Bioorg Med Chem Lett. 2003 May 19;13(10):1783-6. doi: 10.1016/s0960-894x(03)00214-2. Bioorg Med Chem Lett. 2003. PMID: 12729664

9

Proteolyzed matrix as a template for the regulation of tumor progression.

Hornebeck W, Maquart FX. Hornebeck W, et al. Biomed Pharmacother. 2003 Jul-Aug;57(5-6):223-30. doi: 10.1016/s0753-3322(03)00049-0. Biomed Pharmacother. 2003. PMID: 12888258 Review.

10

Protective effect of oleoyl peptide conjugates against elastolysis by neutrophil elastase and kappa elastin-induced monocyte chemotaxis.

Rasoamanantena P, Moczar E, Robert L, Wei SM, Godeau G, Hornebeck W. Rasoamanantena P, et al. Among authors: hornebeck w. Am J Respir Cell Mol Biol. 1993 Jan;8(1):50-5. doi: 10.1165/ajrcmb/8.1.50. Am J Respir Cell Mol Biol. 1993. PMID: 8417756

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