Horn D - Search Results

1

Oligo targeting for profiling drug resistance mutations in the parasitic trypanosomatids.

Altmann S, Rico E, Carvalho S, Ridgway M, Trenaman A, Donnelly H, Tinti M, Wyllie S, Horn D. Altmann S, et al. Among authors: horn d. Nucleic Acids Res. 2022 Aug 12;50(14):e79. doi: 10.1093/nar/gkac319. Nucleic Acids Res. 2022. PMID: 35524555 Free PMC article.

2

Deletion of a trypanosome telomere leads to loss of silencing and progressive loss of terminal DNA in the absence of cell cycle arrest.

Glover L, Alsford S, Beattie C, Horn D. Glover L, et al. Among authors: horn d. Nucleic Acids Res. 2007;35(3):872-80. doi: 10.1093/nar/gkl1100. Epub 2007 Jan 23. Nucleic Acids Res. 2007. PMID: 17251198 Free PMC article.

3

Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes.

Glover L, McCulloch R, Horn D. Glover L, et al. Among authors: horn d. Nucleic Acids Res. 2008 May;36(8):2608-18. doi: 10.1093/nar/gkn104. Epub 2008 Mar 11. Nucleic Acids Res. 2008. PMID: 18334531 Free PMC article.

4

Microhomology-mediated deletion and gene conversion in African trypanosomes.

Glover L, Jun J, Horn D. Glover L, et al. Among authors: horn d. Nucleic Acids Res. 2011 Mar;39(4):1372-80. doi: 10.1093/nar/gkq981. Epub 2010 Oct 21. Nucleic Acids Res. 2011. PMID: 20965968 Free PMC article.

5

Locus-specific control of DNA resection and suppression of subtelomeric VSG recombination by HAT3 in the African trypanosome.

Glover L, Horn D. Glover L, et al. Among authors: horn d. Nucleic Acids Res. 2014 Nov 10;42(20):12600-13. doi: 10.1093/nar/gku900. Epub 2014 Oct 9. Nucleic Acids Res. 2014. PMID: 25300492 Free PMC article.

6

Chimerization at the AQP2-AQP3 locus is the genetic basis of melarsoprol-pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates.

Graf FE, Baker N, Munday JC, de Koning HP, Horn D, Mäser P. Graf FE, et al. Among authors: horn d. Int J Parasitol Drugs Drug Resist. 2015 May 7;5(2):65-8. doi: 10.1016/j.ijpddr.2015.04.002. eCollection 2015 Aug. Int J Parasitol Drugs Drug Resist. 2015. PMID: 26042196 Free PMC article.

7

Comparative genomics of drug resistance in Trypanosoma brucei rhodesiense.

Graf FE, Ludin P, Arquint C, Schmidt RS, Schaub N, Kunz Renggli C, Munday JC, Krezdorn J, Baker N, Horn D, Balmer O, Caccone A, de Koning HP, Mäser P. Graf FE, et al. Among authors: horn d. Cell Mol Life Sci. 2016 Sep;73(17):3387-400. doi: 10.1007/s00018-016-2173-6. Epub 2016 Mar 14. Cell Mol Life Sci. 2016. PMID: 26973180 Free PMC article.

8

Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression.

Maishman L, Obado SO, Alsford S, Bart JM, Chen WM, Ratushny AV, Navarro M, Horn D, Aitchison JD, Chait BT, Rout MP, Field MC. Maishman L, et al. Among authors: horn d. Nucleic Acids Res. 2016 Dec 15;44(22):10554-10570. doi: 10.1093/nar/gkw751. Epub 2016 Sep 12. Nucleic Acids Res. 2016. PMID: 27625397 Free PMC article.

9

The Role of Folate Transport in Antifolate Drug Action in Trypanosoma brucei.

Dewar S, Sienkiewicz N, Ong HB, Wall RJ, Horn D, Fairlamb AH. Dewar S, et al. Among authors: horn d. J Biol Chem. 2016 Nov 18;291(47):24768-24778. doi: 10.1074/jbc.M116.750422. Epub 2016 Oct 4. J Biol Chem. 2016. PMID: 27703008 Free PMC article.

10

Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need.

Field MC, Horn D, Fairlamb AH, Ferguson MA, Gray DW, Read KD, De Rycker M, Torrie LS, Wyatt PG, Wyllie S, Gilbert IH. Field MC, et al. Among authors: horn d. Nat Rev Microbiol. 2017 Feb 27;15(4):217-231. doi: 10.1038/nrmicro.2016.193. Online ahead of print. Nat Rev Microbiol. 2017. PMID: 28239154 Free PMC article. Review.

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