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A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation.
Bonetti L, Horkova V, Longworth J, Guerra L, Kurniawan H, Franchina DG, Soriano-Baguet L, Grusdat M, Spath S, Koncina E, Ewen A, Binsfeld C, Verschueren C, Gérardy JJ, Kobayashi T, Dostert C, Farinelle S, Härm J, Chen Y, Harris IS, Lang PA, Vasiliou V, Waisman A, Letellier E, Becher B, Mittelbronn M, Brenner D. Bonetti L, et al. Among authors: horkova v. bioRxiv [Preprint]. 2023 Jul 7:2023.07.06.547932. doi: 10.1101/2023.07.06.547932. bioRxiv. 2023. PMID: 37489135 Free PMC article. Preprint.
Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions.
Soriano-Baguet L, Grusdat M, Kurniawan H, Benzarti M, Binsfeld C, Ewen A, Longworth J, Bonetti L, Guerra L, Franchina DG, Kobayashi T, Horkova V, Verschueren C, Helgueta S, Gérard D, More TH, Henne A, Dostert C, Farinelle S, Lesur A, Gérardy JJ, Jäger C, Mittelbronn M, Sinkkonen L, Hiller K, Meiser J, Brenner D. Soriano-Baguet L, et al. Among authors: horkova v. Cell Rep. 2023 Mar 28;42(3):112153. doi: 10.1016/j.celrep.2023.112153. Epub 2023 Feb 26. Cell Rep. 2023. PMID: 36848289 Free article.
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells.
Horkova V, Drobek A, Paprckova D, Niederlova V, Prasai A, Uleri V, Glatzova D, Kraller M, Cesnekova M, Janusova S, Salyova E, Tsyklauri O, Kadlecek TA, Krizova K, Platzer R, Schober K, Busch DH, Weiss A, Huppa JB, Stepanek O. Horkova V, et al. Nat Immunol. 2023 Jan;24(1):174-185. doi: 10.1038/s41590-022-01366-0. Epub 2022 Dec 23. Nat Immunol. 2023. PMID: 36564464 Free PMC article.
Self-reactivity of CD8 T-cell clones determines their differentiation status rather than their responsiveness in infections.
Paprckova D, Niederlova V, Moudra A, Drobek A, Pribikova M, Janusova S, Schober K, Neuwirth A, Michalik J, Huranova M, Horkova V, Cesnekova M, Simova M, Prochazka J, Balounova J, Busch DH, Sedlacek R, Schwarzer M, Stepanek O. Paprckova D, et al. Among authors: horkova v. Front Immunol. 2022 Oct 6;13:1009198. doi: 10.3389/fimmu.2022.1009198. eCollection 2022. Front Immunol. 2022. PMID: 36275704 Free PMC article.
A LoCK at the T cell dock.
Horkova V, Stepanek O. Horkova V, et al. Science. 2021 Jun 4;372(6546):1038-1039. doi: 10.1126/science.abj2937. Science. 2021. PMID: 34083474 No abstract available.
The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus.
Karimi MM, Guo Y, Cui X, Pallikonda HA, Horková V, Wang YF, Gil SR, Rodriguez-Esteban G, Robles-Rebollo I, Bruno L, Georgieva R, Patel B, Elliott J, Dore MH, Dauphars D, Krangel MS, Lenhard B, Heyn H, Fisher AG, Štěpánek O, Merkenschlager M. Karimi MM, et al. Among authors: horkova v. Nat Commun. 2021 Jan 4;12(1):99. doi: 10.1038/s41467-020-20306-w. Nat Commun. 2021. PMID: 33397934 Free PMC article.
CD45 functions as a signaling gatekeeper in T cells.
Courtney AH, Shvets AA, Lu W, Griffante G, Mollenauer M, Horkova V, Lo WL, Yu S, Stepanek O, Chakraborty AK, Weiss A. Courtney AH, et al. Among authors: horkova v. Sci Signal. 2019 Oct 22;12(604):eaaw8151. doi: 10.1126/scisignal.aaw8151. Sci Signal. 2019. PMID: 31641081 Free PMC article.
13 results