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Functionally confirmed compound heterozygous ADAM17 missense loss-of-function variants cause neonatal inflammatory skin and bowel disease 1.
Imoto I, Saito M, Suga K, Kohmoto T, Otsu M, Horiuchi K, Nakayama H, Higashiyama S, Sugimoto M, Sasaki A, Homma Y, Shono M, Nakagawa R, Hayabuchi Y, Tange S, Kagami S, Masuda K. Imoto I, et al. Among authors: horiuchi k. Sci Rep. 2021 May 5;11(1):9552. doi: 10.1038/s41598-021-89063-0. Sci Rep. 2021. PMID: 33953303 Free PMC article.
Regulation of osteoarthritis development by ADAM17/Tace in articular cartilage.
Kaneko T, Horiuchi K, Chijimatsu R, Mori D, Nagata K, Omata Y, Yano F, Inui H, Moro T, Tanaka S, Saito T. Kaneko T, et al. Among authors: horiuchi k. J Bone Miner Metab. 2022 Mar;40(2):196-207. doi: 10.1007/s00774-021-01278-3. Epub 2021 Nov 9. J Bone Miner Metab. 2022. PMID: 34751824
ADAM17 protects against elastase-induced emphysema by suppressing CD62L+ leukocyte infiltration in mice.
Suzuki S, Ishii M, Asakura T, Namkoong H, Okamori S, Yagi K, Kamata H, Kusumoto T, Kagawa S, Hegab AE, Yoda M, Horiuchi K, Hasegawa N, Betsuyaku T. Suzuki S, et al. Among authors: horiuchi k. Am J Physiol Lung Cell Mol Physiol. 2020 Jun 1;318(6):L1172-L1182. doi: 10.1152/ajplung.00214.2019. Epub 2020 Mar 4. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32130031 Free article.
922 results