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Serum concentrations of resistin-like molecules beta and gamma are elevated in high-fat-fed and obese db/db mice, with increased production in the intestinal tract and bone marrow.
Shojima N, Ogihara T, Inukai K, Fujishiro M, Sakoda H, Kushiyama A, Katagiri H, Anai M, Ono H, Fukushima Y, Horike N, Viana AY, Uchijima Y, Kurihara H, Asano T. Shojima N, et al. Among authors: horike n. Diabetologia. 2005 May;48(5):984-92. doi: 10.1007/s00125-005-1735-1. Epub 2005 Apr 15. Diabetologia. 2005. PMID: 15834545
Regulation of gut-derived resistin-like molecule beta expression by nutrients.
Fujio J, Kushiyama A, Sakoda H, Fujishiro M, Ogihara T, Fukushima Y, Anai M, Horike N, Kamata H, Uchijima Y, Kurihara H, Asano T. Fujio J, et al. Among authors: horike n. Diabetes Res Clin Pract. 2008 Jan;79(1):2-10. doi: 10.1016/j.diabres.2007.04.015. Epub 2007 Oct 23. Diabetes Res Clin Pract. 2008. PMID: 17936398
Resistin-like molecule beta activates MAPKs, suppresses insulin signaling in hepatocytes, and induces diabetes, hyperlipidemia, and fatty liver in transgenic mice on a high fat diet.
Kushiyama A, Shojima N, Ogihara T, Inukai K, Sakoda H, Fujishiro M, Fukushima Y, Anai M, Ono H, Horike N, Viana AY, Uchijima Y, Nishiyama K, Shimosawa T, Fujita T, Katagiri H, Oka Y, Kurihara H, Asano T. Kushiyama A, et al. Among authors: horike n. J Biol Chem. 2005 Dec 23;280(51):42016-25. doi: 10.1074/jbc.M503065200. Epub 2005 Oct 21. J Biol Chem. 2005. PMID: 16243841 Free article.
Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice.
Koketsu Y, Sakoda H, Fujishiro M, Kushiyama A, Fukushima Y, Ono H, Anai M, Kikuchi T, Fukuda T, Kamata H, Horike N, Uchijima Y, Kurihara H, Asano T. Koketsu Y, et al. Among authors: horike n. Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E719-25. doi: 10.1152/ajpendo.00253.2007. Epub 2008 Feb 12. Am J Physiol Endocrinol Metab. 2008. PMID: 18270303 Free article.
AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver.
Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T. Horike N, et al. J Biol Chem. 2008 Dec 5;283(49):33902-10. doi: 10.1074/jbc.M802537200. Epub 2008 Sep 17. J Biol Chem. 2008. PMID: 18801732 Free PMC article.
Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 associates with insulin receptor substrate-1 and enhances insulin actions and adipogenesis.
Nakatsu Y, Sakoda H, Kushiyama A, Zhang J, Ono H, Fujishiro M, Kikuchi T, Fukushima T, Yoneda M, Ohno H, Horike N, Kanna M, Tsuchiya Y, Kamata H, Nishimura F, Isobe T, Ogihara T, Katagiri H, Oka Y, Takahashi S, Kurihara H, Uchida T, Asano T. Nakatsu Y, et al. Among authors: horike n. J Biol Chem. 2011 Jun 10;286(23):20812-22. doi: 10.1074/jbc.M110.206904. Epub 2011 Mar 17. J Biol Chem. 2011. PMID: 21454638 Free PMC article.
Carboxy-terminal modulator protein induces Akt phosphorylation and activation, thereby enhancing antiapoptotic, glycogen synthetic, and glucose uptake pathways.
Ono H, Sakoda H, Fujishiro M, Anai M, Kushiyama A, Fukushima Y, Katagiri H, Ogihara T, Oka Y, Kamata H, Horike N, Uchijima Y, Kurihara H, Asano T. Ono H, et al. Among authors: horike n. Am J Physiol Cell Physiol. 2007 Nov;293(5):C1576-85. doi: 10.1152/ajpcell.00570.2006. Epub 2007 Jul 5. Am J Physiol Cell Physiol. 2007. PMID: 17615157 Free article.
43 results