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Molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivity.
Nguyen KG, Gillam FB, Hopkins JJ, Jayanthi S, Gundampati RK, Su G, Bear J, Pilkington GR, Jalah R, Felber BK, Liu J, Thallapuranam SK, Zaharoff DA. Nguyen KG, et al. Among authors: hopkins jj. J Biol Chem. 2019 Mar 22;294(12):4412-4424. doi: 10.1074/jbc.RA118.006193. Epub 2019 Jan 22. J Biol Chem. 2019. PMID: 30670588 Free PMC article.
Localized Interleukin-12 for Cancer Immunotherapy.
Nguyen KG, Vrabel MR, Mantooth SM, Hopkins JJ, Wagner ES, Gabaldon TA, Zaharoff DA. Nguyen KG, et al. Among authors: hopkins jj. Front Immunol. 2020 Oct 15;11:575597. doi: 10.3389/fimmu.2020.575597. eCollection 2020. Front Immunol. 2020. PMID: 33178203 Free PMC article. Review.
Chromosome 20p11.2 deletions cause congenital hyperinsulinism via the loss of FOXA2 or its regulatory elements.
Laver TW, Wakeling MN, Caswell RC, Bunce B, Yau D, Männistö JME, Houghton JAL, Hopkins JJ, Weedon MN, Saraff V, Kershaw M, Honey EM, Murphy N, Giri D, Nath S, Tangari Saredo A, Banerjee I, Hussain K, Owens NDL, Flanagan SE. Laver TW, et al. Among authors: hopkins jj. Eur J Hum Genet. 2024 Apr 11. doi: 10.1038/s41431-024-01593-z. Online ahead of print. Eur J Hum Genet. 2024. PMID: 38605124
Non-coding variants disrupting a tissue-specific regulatory element in HK1 cause congenital hyperinsulinism.
Wakeling MN, Owens NDL, Hopkinson JR, Johnson MB, Houghton JAL, Dastamani A, Flaxman CS, Wyatt RC, Hewat TI, Hopkins JJ, Laver TW, van Heugten R, Weedon MN, De Franco E, Patel KA, Ellard S, Morgan NG, Cheesman E, Banerjee I, Hattersley AT, Dunne MJ; International Congenital Hyperinsulinism Consortium; Richardson SJ, Flanagan SE. Wakeling MN, et al. Among authors: hopkins jj. Nat Genet. 2022 Nov;54(11):1615-1620. doi: 10.1038/s41588-022-01204-x. Epub 2022 Nov 4. Nat Genet. 2022. PMID: 36333503 Free PMC article.
Hyperinsulinemic Hypoglycemia Diagnosed in Childhood Can Be Monogenic.
Hopkins JJ, Childs AJ, Houghton JAL, Hewat TI, Atapattu N, Johnson MB, Patel KA, Laver TW, Flanagan SE. Hopkins JJ, et al. J Clin Endocrinol Metab. 2023 Feb 15;108(3):680-687. doi: 10.1210/clinem/dgac604. J Clin Endocrinol Metab. 2023. PMID: 36239000 Free PMC article.
Predicting the immediate impact of national lockdown on neovascular age-related macular degeneration and associated visual morbidity: an INSIGHT Health Data Research Hub for Eye Health report.
Mollan SP, Fu DJ, Chuo CY, Gannon JG, Lee WH, Hopkins JJ, Hughes C, Denniston AK, Keane PA, Cantrell R. Mollan SP, et al. Among authors: hopkins jj. Br J Ophthalmol. 2023 Feb;107(2):267-274. doi: 10.1136/bjophthalmol-2021-319383. Epub 2021 Sep 13. Br J Ophthalmol. 2023. PMID: 34518162 Free PMC article.
End-of-Study Results for the Ladder Phase 2 Trial of the Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration.
Khanani AM, Callanan D, Dreyer R, Chen S, Howard JG, Hopkins JJ, Lin CY, Lorenz-Candlin M, Makadia S, Patel S, Tam T, Gune S; of the Ladder Investigators. Khanani AM, et al. Among authors: hopkins jj. Ophthalmol Retina. 2021 Aug;5(8):775-787. doi: 10.1016/j.oret.2020.11.004. Epub 2020 Nov 18. Ophthalmol Retina. 2021. PMID: 33217618 Free article. Clinical Trial.
40 results