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3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma.
Maurer M, Su T, Saal LH, Koujak S, Hopkins BD, Barkley CR, Wu J, Nandula S, Dutta B, Xie Y, Chin YR, Kim DI, Ferris JS, Gruvberger-Saal SK, Laakso M, Wang X, Memeo L, Rojtman A, Matos T, Yu JS, Cordon-Cardo C, Isola J, Terry MB, Toker A, Mills GB, Zhao JJ, Murty VV, Hibshoosh H, Parsons R. Maurer M, et al. Among authors: hopkins bd. Cancer Res. 2009 Aug 1;69(15):6299-306. doi: 10.1158/0008-5472.CAN-09-0820. Epub 2009 Jul 14. Cancer Res. 2009. PMID: 19602588 Free PMC article.
Gab2-mediated signaling promotes melanoma metastasis.
Horst B, Gruvberger-Saal SK, Hopkins BD, Bordone L, Yang Y, Chernoff KA, Uzoma I, Schwipper V, Liebau J, Nowak NJ, Brunner G, Owens D, Rimm DL, Parsons R, Celebi JT. Horst B, et al. Among authors: hopkins bd. Am J Pathol. 2009 Apr;174(4):1524-33. doi: 10.2353/ajpath.2009.080543. Am J Pathol. 2009. PMID: 19342374 Free PMC article.
Survival factor NFIL3 restricts FOXO-induced gene expression in cancer.
Keniry M, Pires MM, Mense S, Lefebvre C, Gan B, Justiano K, Lau YK, Hopkins B, Hodakoski C, Koujak S, Toole J, Fenton F, Calahan A, Califano A, DePinho RA, Maurer M, Parsons R. Keniry M, et al. Genes Dev. 2013 Apr 15;27(8):916-27. doi: 10.1101/gad.214049.113. Genes Dev. 2013. PMID: 23630076 Free PMC article.
A secreted PTEN phosphatase that enters cells to alter signaling and survival.
Hopkins BD, Fine B, Steinbach N, Dendy M, Rapp Z, Shaw J, Pappas K, Yu JS, Hodakoski C, Mense S, Klein J, Pegno S, Sulis ML, Goldstein H, Amendolara B, Lei L, Maurer M, Bruce J, Canoll P, Hibshoosh H, Parsons R. Hopkins BD, et al. Science. 2013 Jul 26;341(6144):399-402. doi: 10.1126/science.1234907. Epub 2013 Jun 6. Science. 2013. PMID: 23744781 Free PMC article.
PTEN function: the long and the short of it.
Hopkins BD, Hodakoski C, Barrows D, Mense SM, Parsons RE. Hopkins BD, et al. Trends Biochem Sci. 2014 Apr;39(4):183-90. doi: 10.1016/j.tibs.2014.02.006. Epub 2014 Mar 18. Trends Biochem Sci. 2014. PMID: 24656806 Free PMC article. Review.
Metformin and erlotinib synergize to inhibit basal breast cancer.
Lau YK, Du X, Rayannavar V, Hopkins B, Shaw J, Bessler E, Thomas T, Pires MM, Keniry M, Parsons RE, Cremers S, Szabolcs M, Maurer MA. Lau YK, et al. Oncotarget. 2014 Nov 15;5(21):10503-17. doi: 10.18632/oncotarget.2391. Oncotarget. 2014. PMID: 25361177 Free PMC article.
58 results