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Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis.
Jarvis JN, Lawrence DS, Meya DB, Kagimu E, Kasibante J, Mpoza E, Rutakingirwa MK, Ssebambulidde K, Tugume L, Rhein J, Boulware DR, Mwandumba HC, Moyo M, Mzinganjira H, Kanyama C, Hosseinipour MC, Chawinga C, Meintjes G, Schutz C, Comins K, Singh A, Muzoora C, Jjunju S, Nuwagira E, Mosepele M, Leeme T, Siamisang K, Ndhlovu CE, Hlupeni A, Mutata C, van Widenfelt E, Chen T, Wang D, Hope W, Boyer-Chammard T, Loyse A, Molloy SF, Youssouf N, Lortholary O, Lalloo DG, Jaffar S, Harrison TS; Ambition Study Group. Jarvis JN, et al. Among authors: hope w. N Engl J Med. 2022 Mar 24;386(12):1109-1120. doi: 10.1056/NEJMoa2111904. N Engl J Med. 2022. PMID: 35320642 Free PMC article. Clinical Trial.
Short-course High-dose Liposomal Amphotericin B for Human Immunodeficiency Virus-associated Cryptococcal Meningitis: A Phase 2 Randomized Controlled Trial.
Jarvis JN, Leeme TB, Molefi M, Chofle AA, Bidwell G, Tsholo K, Tlhako N, Mawoko N, Patel RKK, Tenforde MW, Muthoga C, Bisson GP, Kidola J, Changalucha J, Lawrence D, Jaffar S, Hope W, Molloy SLF, Harrison TS. Jarvis JN, et al. Among authors: hope w. Clin Infect Dis. 2019 Jan 18;68(3):393-401. doi: 10.1093/cid/ciy515. Clin Infect Dis. 2019. PMID: 29945252 Free PMC article. Clinical Trial.
AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial.
Lawrence DS, Youssouf N, Molloy SF, Alanio A, Alufandika M, Boulware DR, Boyer-Chammard T, Chen T, Dromer F, Hlupeni A, Hope W, Hosseinipour MC, Kanyama C, Lortholary O, Loyse A, Meya DB, Mosepele M, Muzoora C, Mwandumba HC, Ndhlovu CE, Niessen L, Schutz C, Stott KE, Wang D, Lalloo DG, Meintjes G, Jaffar S, Harrison TS, Jarvis JN. Lawrence DS, et al. Among authors: hope w. Trials. 2018 Nov 23;19(1):649. doi: 10.1186/s13063-018-3026-4. Trials. 2018. PMID: 30470259 Free PMC article.
Cryptococcal meningoencephalitis: time for action.
Stott KE, Loyse A, Jarvis JN, Alufandika M, Harrison TS, Mwandumba HC, Day JN, Lalloo DG, Bicanic T, Perfect JR, Hope W. Stott KE, et al. Among authors: hope w. Lancet Infect Dis. 2021 Sep;21(9):e259-e271. doi: 10.1016/S1473-3099(20)30771-4. Epub 2021 Apr 16. Lancet Infect Dis. 2021. PMID: 33872594 Review.
AMBITION-cm: intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa: study protocol for a randomized controlled trial.
Molefi M, Chofle AA, Molloy SF, Kalluvya S, Changalucha JM, Cainelli F, Leeme T, Lekwape N, Goldberg DW, Haverkamp M, Bisson GP, Perfect JR, Letang E, Fenner L, Meintjes G, Burton R, Makadzange T, Ndhlovu CE, Hope W, Harrison TS, Jarvis JN. Molefi M, et al. Among authors: hope w. Trials. 2015 Jun 17;16:276. doi: 10.1186/s13063-015-0799-6. Trials. 2015. PMID: 26081985 Free PMC article. Clinical Trial.
Correction to: AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial.
Lawrence DS, Youssouf N, Molloy SF, Alanio A, Alufandika M, Boulware DR, Boyer-Chammard T, Chen T, Dromer F, Hlupeni A, Hope W, Hosseinipour MC, Kanyama C, Lortholary O, Loyse A, Meya DB, Mosepele M, Muzoora C, Mwandumba HC, Ndhlovu CE, Niessen L, Schutz C, Stott KE, Wang D, Lalloo DG, Meintjes G, Jaffar S, Harrison TS, Jarvis JN. Lawrence DS, et al. Among authors: hope w. Trials. 2019 Jan 14;20(1):48. doi: 10.1186/s13063-018-3155-9. Trials. 2019. PMID: 30642386 Free PMC article.
Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis.
Stone NR, Rhodes J, Fisher MC, Mfinanga S, Kivuyo S, Rugemalila J, Segal ES, Needleman L, Molloy SF, Kwon-Chung J, Harrison TS, Hope W, Berman J, Bicanic T. Stone NR, et al. Among authors: hope w. J Clin Invest. 2019 Mar 1;129(3):999-1014. doi: 10.1172/JCI124516. Epub 2019 Jan 28. J Clin Invest. 2019. PMID: 30688656 Free PMC article. Clinical Trial.
Population Pharmacokinetic Model and Meta-analysis of Outcomes of Amphotericin B Deoxycholate Use in Adults with Cryptococcal Meningitis.
Stott KE, Beardsley J, Whalley S, Kibengo FM, Mai NTH, Tùng NLN, Cuc NTK, Kolamunnage-Dona R, Hope W, Day J. Stott KE, et al. Among authors: hope w. Antimicrob Agents Chemother. 2018 Jun 26;62(7):e02526-17. doi: 10.1128/AAC.02526-17. Print 2018 Jul. Antimicrob Agents Chemother. 2018. PMID: 29735567 Free PMC article.
480 results