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TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo.
Kim J, Bose D, Araínga M, Haque MR, Fennessey CM, Caddell RA, Thomas Y, Ferrell DE, Ali S, Grody E, Goyal Y, Cicala C, Arthos J, Keele BF, Vaccari M, Lorenzo-Redondo R, Hope TJ, Villinger F, Martinelli E. Kim J, et al. Among authors: hope tj. Nat Commun. 2024 Feb 14;15(1):1348. doi: 10.1038/s41467-024-45555-x. Nat Commun. 2024. PMID: 38355731 Free PMC article.
Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo.
Samer S, Thomas Y, Araínga M, Carter C, Shirreff LM, Arif MS, Avita JM, Frank I, McRaven MD, Thuruthiyil CT, Heybeli VB, Anderson MR, Owen B, Gaisin A, Bose D, Simons LM, Hultquist JF, Arthos J, Cicala C, Sereti I, Santangelo PJ, Lorenzo-Redondo R, Hope TJ, Villinger FJ, Martinelli E. Samer S, et al. Among authors: hope tj. JCI Insight. 2022 Nov 8;7(21):e162290. doi: 10.1172/jci.insight.162290. JCI Insight. 2022. PMID: 36125890 Free PMC article.
Blocking α4β7 integrin delays viral rebound in SHIVSF162P3-infected macaques treated with anti-HIV broadly neutralizing antibodies.
Frank I, Cigoli M, Arif MS, Fahlberg MD, Maldonado S, Calenda G, Pegu A, Yang ES, Rawi R, Chuang GY, Geng H, Liu C, Zhou T, Kwong PD, Arthos J, Cicala C, Grasperge BF, Blanchard JL, Gettie A, Fennessey CM, Keele BF, Vaccari M, Hope TJ, Fauci AS, Mascola JR, Martinelli E. Frank I, et al. Among authors: hope tj. Sci Transl Med. 2021 Aug 18;13(607):eabf7201. doi: 10.1126/scitranslmed.abf7201. Sci Transl Med. 2021. PMID: 34408080 Free PMC article.
Localization of infection in neonatal rhesus macaques after oral viral challenge.
Taylor RA, McRaven MD, Carias AM, Anderson MR, Matias E, Araínga M, Allen EJ, Rogers KA, Gupta S, Kulkarni V, Lakhashe S, Lorenzo-Redondo R, Thomas Y, Strickland A, Villinger FJ, Ruprecht RM, Hope TJ. Taylor RA, et al. Among authors: hope tj. PLoS Pathog. 2021 Nov 18;17(11):e1009855. doi: 10.1371/journal.ppat.1009855. eCollection 2021 Nov. PLoS Pathog. 2021. PMID: 34793582 Free PMC article.
TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo.
Kime J, Bose D, Arainga M, Haque MR, Fennessey CM, Caddell RA, Thomas Y, Ferrell DE, Ali S, Grody E, Goyal Y, Cicala C, Arthos J, Keele BF, Vaccari M, Lorenzo-Redondo R, Hope TJ, Villinger FJ, Marinelli E. Kime J, et al. Among authors: hope tj. bioRxiv [Preprint]. 2023 Dec 15:2023.09.05.556422. doi: 10.1101/2023.09.05.556422. bioRxiv. 2023. PMID: 38014094 Free PMC article. Updated. Preprint.
Development of an In Vivo Probe to Track SARS-CoV-2 Infection in Rhesus Macaques.
Madden PJ, Arif MS, Becker ME, McRaven MD, Carias AM, Lorenzo-Redondo R, Xiao S, Midkiff CC, Blair RV, Potter EL, Martin-Sancho L, Dodson A, Martinelli E, Todd JM, Villinger FJ, Chanda SK, Aye PP, Roy CJ, Roederer M, Lewis MG, Veazey RS, Hope TJ. Madden PJ, et al. Among authors: hope tj. Front Immunol. 2021 Dec 24;12:810047. doi: 10.3389/fimmu.2021.810047. eCollection 2021. Front Immunol. 2021. PMID: 35003140 Free PMC article.
Simian Immunodeficiency Virus Susceptibility, Immunology, and Microbiome in the Female Genital Tract of Adolescent Versus Adult Pigtail Macaques.
Berard AR, Miller C, Araínga M, Broedlow CA, Noël-Romas L, Schifanella L, Hensley-McBain T, Roederer A, Driscoll CB, Coronado E, Manuzak J, McKinnon LR, Villinger F, Hope TJ, Burgener AD, Klatt NR. Berard AR, et al. Among authors: hope tj. AIDS Res Hum Retroviruses. 2021 Jul;37(7):510-522. doi: 10.1089/AID.2020.0271. Epub 2021 Jun 22. AIDS Res Hum Retroviruses. 2021. PMID: 33446027 Free PMC article.
PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure.
Taylor RA, Xiao S, Carias AM, McRaven MD, Thakkar DN, Araínga M, Allen EJ, Rogers KA, Kumarapperuma SC, Gong S, Fought AJ, Anderson MR, Thomas Y, Schneider JR, Goins B, Fox P, Villinger FJ, Ruprecht RM, Hope TJ. Taylor RA, et al. Among authors: hope tj. PLoS Pathog. 2021 Jun 1;17(6):e1009632. doi: 10.1371/journal.ppat.1009632. eCollection 2021 Jun. PLoS Pathog. 2021. PMID: 34061907 Free PMC article.
222 results