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Oncostatin M triggers brain inflammation by compromising blood-brain barrier integrity.
Hermans D, Houben E, Baeten P, Slaets H, Janssens K, Hoeks C, Hosseinkhani B, Duran G, Bormans S, Gowing E, Hoornaert C, Beckers L, Fung WK, Schroten H, Ishikawa H, Fraussen J, Thoelen R, de Vries HE, Kooij G, Zandee S, Prat A, Hellings N, Broux B. Hermans D, et al. Among authors: hoornaert c. Acta Neuropathol. 2022 Aug;144(2):259-281. doi: 10.1007/s00401-022-02445-0. Epub 2022 Jun 6. Acta Neuropathol. 2022. PMID: 35666306
DICAM promotes TH17 lymphocyte trafficking across the blood-brain barrier during autoimmune neuroinflammation.
Charabati M, Grasmuck C, Ghannam S, Bourbonnière L, Fournier AP, Lécuyer MA, Tastet O, Kebir H, Rébillard RM, Hoornaert C, Gowing E, Larouche S, Fortin O, Pittet C, Filali-Mouhim A, Lahav B, Moumdjian R, Bouthillier A, Girard M, Duquette P, Cayrol R, Peelen E, Quintana FJ, Antel JP, Flügel A, Larochelle C, Arbour N, Zandee S, Prat A. Charabati M, et al. Among authors: hoornaert c. Sci Transl Med. 2022 Jan 5;14(626):eabj0473. doi: 10.1126/scitranslmed.abj0473. Epub 2022 Jan 5. Sci Transl Med. 2022. PMID: 34985970
Combination of cuprizone and experimental autoimmune encephalomyelitis to study inflammatory brain lesion formation and progression.
Rüther BJ, Scheld M, Dreymueller D, Clarner T, Kress E, Brandenburg LO, Swartenbroekx T, Hoornaert C, Ponsaerts P, Fallier-Becker P, Beyer C, Rohr SO, Schmitz C, Chrzanowski U, Hochstrasser T, Nyamoya S, Kipp M. Rüther BJ, et al. Among authors: hoornaert c. Glia. 2017 Dec;65(12):1900-1913. doi: 10.1002/glia.23202. Epub 2017 Aug 24. Glia. 2017. PMID: 28836302
Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model.
Le Blon D, Guglielmetti C, Hoornaert C, Quarta A, Daans J, Dooley D, Lemmens E, Praet J, De Vocht N, Reekmans K, Santermans E, Hens N, Goossens H, Verhoye M, Van der Linden A, Berneman Z, Hendrix S, Ponsaerts P. Le Blon D, et al. Among authors: hoornaert c. J Neuroinflammation. 2016 Nov 9;13(1):288. doi: 10.1186/s12974-016-0756-7. J Neuroinflammation. 2016. PMID: 27829467 Free PMC article.
Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages.
Guglielmetti C, Le Blon D, Santermans E, Salas-Perdomo A, Daans J, De Vocht N, Shah D, Hoornaert C, Praet J, Peerlings J, Kara F, Bigot C, Mai Z, Goossens H, Hens N, Hendrix S, Verhoye M, Planas AM, Berneman Z, van der Linden A, Ponsaerts P. Guglielmetti C, et al. Among authors: hoornaert c. Glia. 2016 Dec;64(12):2181-2200. doi: 10.1002/glia.23053. Epub 2016 Sep 29. Glia. 2016. PMID: 27685637
In Vivo Interleukin-13-Primed Macrophages Contribute to Reduced Alloantigen-Specific T Cell Activation and Prolong Immunological Survival of Allogeneic Mesenchymal Stem Cell Implants.
Hoornaert CJ, Luyckx E, Reekmans K, Dhainaut M, Guglielmetti C, Le Blon D, Dooley D, Fransen E, Daans J, Verbeeck L, Quarta A, De Vocht N, Lemmens E, Goossens H, Van der Linden A, Roobrouck VD, Verfaillie C, Hendrix S, Moser M, Berneman ZN, Ponsaerts P. Hoornaert CJ, et al. Stem Cells. 2016 Jul;34(7):1971-84. doi: 10.1002/stem.2360. Epub 2016 Mar 28. Stem Cells. 2016. PMID: 26992046
Quantitative and phenotypic analysis of mesenchymal stromal cell graft survival and recognition by microglia and astrocytes in mouse brain.
De Vocht N, Lin D, Praet J, Hoornaert C, Reekmans K, Le Blon D, Daans J, Pauwels P, Goossens H, Hens N, Berneman Z, Van der Linden A, Ponsaerts P. De Vocht N, et al. Among authors: hoornaert c. Immunobiology. 2013 May;218(5):696-705. doi: 10.1016/j.imbio.2012.08.266. Epub 2012 Aug 9. Immunobiology. 2013. PMID: 22944251 Free article.
31 results