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The SARS-CoV-2 spike protein binds and modulates estrogen receptors.
Solis O, Beccari AR, Iaconis D, Talarico C, Ruiz-Bedoya CA, Nwachukwu JC, Cimini A, Castelli V, Bertini R, Montopoli M, Cocetta V, Borocci S, Prandi IG, Flavahan K, Bahr M, Napiorkowski A, Chillemi G, Ooka M, Yang X, Zhang S, Xia M, Zheng W, Bonaventura J, Pomper MG, Hooper JE, Morales M, Rosenberg AZ, Nettles KW, Jain SK, Allegretti M, Michaelides M. Solis O, et al. Among authors: hooper je. Sci Adv. 2022 Dec 2;8(48):eadd4150. doi: 10.1126/sciadv.add4150. Epub 2022 Nov 30. Sci Adv. 2022. PMID: 36449624 Free PMC article.
Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs.
Won T, Wood MK, Hughes DM, Talor MV, Ma Z, Schneider J, Skinner JT, Asady B, Goerlich E, Halushka MK, Hays AG, Kim DH, Parikh CR, Rosenberg AZ, Coppens I, Johns RA, Gilotra NA, Hooper JE, Pekosz A, Čiháková D. Won T, et al. Among authors: hooper je. EBioMedicine. 2022 Jan;75:103812. doi: 10.1016/j.ebiom.2022.103812. Epub 2022 Jan 13. EBioMedicine. 2022. PMID: 35033854 Free PMC article.
Fatal SARS-CoV-2 Inflammatory Syndrome and Myocarditis in an Adolescent: A Case Report.
Beaudry JT, Dietrick B, Lammert DB, Constas A, McCaw J, Hammond J, Buendia M, Stein JE, Pekosz A, Schuette J, Mostafa HH, Hooper JE, Bernier M, Agwu A, Feldman LS. Beaudry JT, et al. Among authors: hooper je. Pediatr Infect Dis J. 2021 Feb 1;40(2):e72-e76. doi: 10.1097/INF.0000000000002978. Pediatr Infect Dis J. 2021. PMID: 33181783 Free PMC article.
IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function.
Casciola-Rosen L, Thiemann DR, Andrade F, Trejo-Zambrano MI, Leonard EK, Spangler JB, Skinner NE, Bailey J, Yegnasubramanian S, Wang R, Vaghasia AM, Gupta A, Cox AL, Ray SC, Linville RM, Guo Z, Searson PC, Machamer CE, Desiderio S, Sauer LM, Laeyendecker O, Garibaldi BT, Gao L, Damarla M, Hassoun PM, Hooper JE, Mecoli CA, Christopher-Stine L, Gutierrez-Alamillo L, Yang Q, Hines D, Clarke WA, Rothman RE, Pekosz A, Fenstermacher KZ, Wang Z, Zeger SL, Rosen A. Casciola-Rosen L, et al. Among authors: hooper je. JCI Insight. 2022 May 9;7(9):e158362. doi: 10.1172/jci.insight.158362. JCI Insight. 2022. PMID: 35349483 Free PMC article.
120 results