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Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease.
Pickett EK, Herrmann AG, McQueen J, Abt K, Dando O, Tulloch J, Jain P, Dunnett S, Sohrabi S, Fjeldstad MP, Calkin W, Murison L, Jackson RJ, Tzioras M, Stevenson A, d'Orange M, Hooley M, Davies C, Colom-Cadena M, Anton-Fernandez A, King D, Oren I, Rose J, McKenzie CA, Allison E, Smith C, Hardt O, Henstridge CM, Hardingham GE, Spires-Jones TL. Pickett EK, et al. Among authors: hooley m. Cell Rep. 2019 Dec 10;29(11):3592-3604.e5. doi: 10.1016/j.celrep.2019.11.044. Cell Rep. 2019. PMID: 31825838 Free PMC article.
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.
Jiwaji Z, Tiwari SS, Avilés-Reyes RX, Hooley M, Hampton D, Torvell M, Johnson DA, McQueen J, Baxter P, Sabari-Sankar K, Qiu J, He X, Fowler J, Febery J, Gregory J, Rose J, Tulloch J, Loan J, Story D, McDade K, Smith AM, Greer P, Ball M, Kind PC, Matthews PM, Smith C, Dando O, Spires-Jones TL, Johnson JA, Chandran S, Hardingham GE. Jiwaji Z, et al. Among authors: hooley m. Nat Commun. 2022 Jan 10;13(1):135. doi: 10.1038/s41467-021-27702-w. Nat Commun. 2022. PMID: 35013236 Free PMC article.
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease.
Colom-Cadena M, Toombs J, Simzer E, Holt K, McGeachan R, Tulloch J, Jackson RJ, Catterson JH, Spires-Jones MP, Rose J, Waybright L, Caggiano AO, King D, Gobbo F, Davies C, Hooley M, Dunnett S, Tempelaar R, Meftah S, Tzioras M, Hamby ME, Izzo NJ, Catalano SM, Durrant CS, Smith C, Dando O, Spires-Jones TL. Colom-Cadena M, et al. Among authors: hooley m. Acta Neuropathol. 2024 Feb 6;147(1):32. doi: 10.1007/s00401-023-02679-6. Acta Neuropathol. 2024. PMID: 38319380 Free PMC article.
Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion.
Pagnon de la Vega M, Syvänen S, Giedraitis V, Hooley M, Konstantinidis E, Meier SR, Rokka J, Eriksson J, Aguilar X, Spires-Jones TL, Lannfelt L, Nilsson LNG, Erlandsson A, Hultqvist G, Ingelsson M, Sehlin D. Pagnon de la Vega M, et al. Among authors: hooley m. Acta Neuropathol Commun. 2024 Feb 5;12(1):22. doi: 10.1186/s40478-024-01734-x. Acta Neuropathol Commun. 2024. PMID: 38317196 Free PMC article.
36 results