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Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.
Tsai PY, Lee MS, Jadhav U, Naqvi I, Madha S, Adler A, Mistry M, Naumenko S, Lewis CA, Hitchcock DS, Roberts FR, DelNero P, Hank T, Honselmann KC, Morales Oyarvide V, Mino-Kenudson M, Clish CB, Shivdasani RA, Kalaany NY. Tsai PY, et al. Among authors: honselmann kc. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2003014118. doi: 10.1073/pnas.2003014118. Proc Natl Acad Sci U S A. 2021. PMID: 33653947 Free PMC article.
Tumor engraftment in patient-derived xenografts of pancreatic ductal adenocarcinoma is associated with adverse clinicopathological features and poor survival.
Pergolini I, Morales-Oyarvide V, Mino-Kenudson M, Honselmann KC, Rosenbaum MW, Nahar S, Kem M, Ferrone CR, Lillemoe KD, Bardeesy N, Ryan DP, Thayer SP, Warshaw AL, Fernández-Del Castillo C, Liss AS. Pergolini I, et al. Among authors: honselmann kc. PLoS One. 2017 Aug 30;12(8):e0182855. doi: 10.1371/journal.pone.0182855. eCollection 2017. PLoS One. 2017. PMID: 28854237 Free PMC article.
Neoplastic-Stromal Cell Cross-talk Regulates Matrisome Expression in Pancreatic Cancer.
Honselmann KC, Finetti P, Birnbaum DJ, Monsalve CS, Wellner UF, Begg SKS, Nakagawa A, Hank T, Li A, Goldsworthy MA, Sharma H, Bertucci F, Birnbaum D, Tai E, Ligorio M, Ting DT, Schilling O, Biniossek ML, Bronsert P, Ferrone CR, Keck T, Mino-Kenudson M, Lillemoe KD, Warshaw AL, Fernández-Del Castillo C, Liss AS. Honselmann KC, et al. Mol Cancer Res. 2020 Dec;18(12):1889-1902. doi: 10.1158/1541-7786.MCR-20-0439. Epub 2020 Sep 1. Mol Cancer Res. 2020. PMID: 32873625
Predictors of Resectability and Survival in Patients With Borderline and Locally Advanced Pancreatic Cancer who Underwent Neoadjuvant Treatment With FOLFIRINOX.
Michelakos T, Pergolini I, Castillo CF, Honselmann KC, Cai L, Deshpande V, Wo JY, Ryan DP, Allen JN, Blaszkowsky LS, Clark JW, Murphy JE, Nipp RD, Parikh A, Qadan M, Warshaw AL, Hong TS, Lillemoe KD, Ferrone CR. Michelakos T, et al. Among authors: honselmann kc. Ann Surg. 2019 Apr;269(4):733-740. doi: 10.1097/SLA.0000000000002600. Ann Surg. 2019. PMID: 29227344
Implications of Perineural Invasion on Disease Recurrence and Survival After Pancreatectomy for Pancreatic Head Ductal Adenocarcinoma.
Crippa S, Pergolini I, Javed AA, Honselmann KC, Weiss MJ, Di Salvo F, Burkhart R, Zamboni G, Belfiori G, Ferrone CR, Rubini C, Yu J, Gasparini G, Qadan M, He J, Lillemoe KD, Castillo CF, Wolfgang CL, Falconi M. Crippa S, et al. Among authors: honselmann kc. Ann Surg. 2022 Aug 1;276(2):378-385. doi: 10.1097/SLA.0000000000004464. Epub 2020 Oct 19. Ann Surg. 2022. PMID: 33086324
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