Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

17 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease.
Czarnota-Łydka K, Sudoł-Tałaj S, Kucwaj-Brysz K, Kurczab R, Satała G, de Candia M, Samarelli F, Altomare CD, Carocci A, Barbarossa A, Żesławska E, Głuch-Lutwin M, Mordyl B, Kubacka M, Wilczyńska-Zawal N, Jastrzębska-Więsek M, Partyka A, Khan N, Więcek M, Nitek W, Honkisz-Orzechowska E, Latacz G, Wesołowska A, Carrieri A, Handzlik J. Czarnota-Łydka K, et al. Among authors: honkisz orzechowska e. Eur J Med Chem. 2023 Nov 5;259:115695. doi: 10.1016/j.ejmech.2023.115695. Epub 2023 Jul 30. Eur J Med Chem. 2023. PMID: 37567058 Free article.
The Phenoxyalkyltriazine Antagonists for 5-HT6 Receptor with Promising Procognitive and Pharmacokinetic Properties In Vivo in Search for a Novel Therapeutic Approach to Dementia Diseases.
Sudoł S, Cios A, Jastrzębska-Więsek M, Honkisz-Orzechowska E, Mordyl B, Wilczyńska-Zawal N, Satała G, Kucwaj-Brysz K, Partyka A, Latacz G, Olejarz-Maciej A, Wesołowska A, Handzlik J. Sudoł S, et al. Int J Mol Sci. 2021 Oct 5;22(19):10773. doi: 10.3390/ijms221910773. Int J Mol Sci. 2021. PMID: 34639113 Free PMC article.
Seleno-vs. thioether triazine derivatives in search for new anticancer agents overcoming multidrug resistance in lymphoma.
Ali W, Garbo S, Kincses A, Nové M, Spengler G, Di Bello E, Honkisz-Orzechowska E, Karcz T, Szymańska E, Żesławska E, Starek M, Dąbrowska M, Nitek W, Kucwaj-Brysz K, Pyka P, Fioravanti R, Jacob C, Battistelli C, Zwergel C, Handzlik J. Ali W, et al. Eur J Med Chem. 2022 Dec 5;243:114761. doi: 10.1016/j.ejmech.2022.114761. Epub 2022 Sep 19. Eur J Med Chem. 2022. PMID: 36179403
New Triazine Derivatives as Serotonin 5-HT6 Receptor Ligands.
Łażewska D, Więcek M, Satała G, Chałupnik P, Żesławska E, Honkisz-Orzechowska E, Tarasek M, Latacz G, Nitek W, Szymańska E, Handzlik J. Łażewska D, et al. Among authors: honkisz orzechowska e. Molecules. 2023 Jan 22;28(3):1108. doi: 10.3390/molecules28031108. Molecules. 2023. PMID: 36770774 Free PMC article.
Discovery of phenylselenoether-hydantoin hybrids as ABCB1 efflux pump modulating agents with cytotoxic and antiproliferative actions in resistant T-lymphoma.
Ali W, Spengler G, Kincses A, Nové M, Battistelli C, Latacz G, Starek M, Dąbrowska M, Honkisz-Orzechowska E, Romanelli A, Rasile MM, Szymańska E, Jacob C, Zwergel C, Handzlik J. Ali W, et al. Eur J Med Chem. 2020 Aug 15;200:112435. doi: 10.1016/j.ejmech.2020.112435. Epub 2020 May 15. Eur J Med Chem. 2020. PMID: 32505850
Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT6 receptor with anti-aggregation properties against amyloid-beta and tau.
Wichur T, Pasieka A, Godyń J, Panek D, Góral I, Latacz G, Honkisz-Orzechowska E, Bucki A, Siwek A, Głuch-Lutwin M, Knez D, Brazzolotto X, Gobec S, Kołaczkowski M, Sabate R, Malawska B, Więckowska A. Wichur T, et al. Eur J Med Chem. 2021 Dec 5;225:113783. doi: 10.1016/j.ejmech.2021.113783. Epub 2021 Aug 19. Eur J Med Chem. 2021. PMID: 34461507 Free article.
Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease.
Godyń J, Zaręba P, Łażewska D, Stary D, Reiner-Link D, Frank A, Latacz G, Mogilski S, Kaleta M, Doroz-Płonka A, Lubelska A, Honkisz-Orzechowska E, Olejarz-Maciej A, Handzlik J, Stark H, Kieć-Kononowicz K, Malawska B, Bajda M. Godyń J, et al. Bioorg Chem. 2021 Sep;114:105129. doi: 10.1016/j.bioorg.2021.105129. Epub 2021 Jun 28. Bioorg Chem. 2021. PMID: 34217977 Free article.
17 results