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Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer.
Joanito I, Wirapati P, Zhao N, Nawaz Z, Yeo G, Lee F, Eng CLP, Macalinao DC, Kahraman M, Srinivasan H, Lakshmanan V, Verbandt S, Tsantoulis P, Gunn N, Venkatesh PN, Poh ZW, Nahar R, Oh HLJ, Loo JM, Chia S, Cheow LF, Cheruba E, Wong MT, Kua L, Chua C, Nguyen A, Golovan J, Gan A, Lim WJ, Guo YA, Yap CK, Tay B, Hong Y, Chong DQ, Chok AY, Park WY, Han S, Chang MH, Seow-En I, Fu C, Mathew R, Toh EL, Hong LZ, Skanderup AJ, DasGupta R, Ong CJ, Lim KH, Tan EKW, Koo SL, Leow WQ, Tejpar S, Prabhakar S, Tan IB. Joanito I, et al. Among authors: hong lz, hong y. Nat Genet. 2022 Jul;54(7):963-975. doi: 10.1038/s41588-022-01100-4. Epub 2022 Jun 30. Nat Genet. 2022. PMID: 35773407 Free PMC article.
Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer.
Lee HO, Hong Y, Etlioglu HE, Cho YB, Pomella V, Van den Bosch B, Vanhecke J, Verbandt S, Hong H, Min JW, Kim N, Eum HH, Qian J, Boeckx B, Lambrechts D, Tsantoulis P, De Hertogh G, Chung W, Lee T, An M, Shin HT, Joung JG, Jung MH, Ko G, Wirapati P, Kim SH, Kim HC, Yun SH, Tan IBH, Ranjan B, Lee WY, Kim TY, Choi JK, Kim YJ, Prabhakar S, Tejpar S, Park WY. Lee HO, et al. Among authors: hong y, hong h. Nat Genet. 2020 Jun;52(6):594-603. doi: 10.1038/s41588-020-0636-z. Epub 2020 May 25. Nat Genet. 2020. PMID: 32451460
Single cell dynamics of tumor specificity vs bystander activity in CD8+ T cells define the diverse immune landscapes in colorectal cancer.
Borràs DM, Verbandt S, Ausserhofer M, Sturm G, Lim J, Verge GA, Vanmeerbeek I, Laureano RS, Govaerts J, Sprooten J, Hong Y, Wall R, De Hertogh G, Sagaert X, Bislenghi G, D'Hoore A, Wolthuis A, Finotello F, Park WY, Naulaerts S, Tejpar S, Garg AD. Borràs DM, et al. Among authors: hong y. Cell Discov. 2023 Nov 15;9(1):114. doi: 10.1038/s41421-023-00605-4. Cell Discov. 2023. PMID: 37968259 Free PMC article.
Cancer cells undergoing epigenetic transition show short-term resistance and are transformed into cells with medium-term resistance by drug treatment.
Poojan S, Bae SH, Min JW, Lee EY, Song Y, Kim HY, Sim HW, Kang EK, Kim YH, Lee HO, Hong Y, Park WY, Jang H, Hong KM. Poojan S, et al. Among authors: hong km, hong y. Exp Mol Med. 2020 Jul;52(7):1102-1115. doi: 10.1038/s12276-020-0464-3. Epub 2020 Jul 13. Exp Mol Med. 2020. PMID: 32661348 Free PMC article.
Comprehensive profiling of DNA methylation in Korean patients with colorectal cancer.
Shim H, Jang K, Bang YH, Chu HBK, Kang J, Lee JY, Cho S, Lee HS, Jeon J, Hwang T, Joe S, Lim J, Choi JH, Joo EH, Park K, Moon JH, Han KY, Hong Y, Lee WY, Kim HC, Yun SH, Cho YB, Park YA, Huh JW, Shin JK, Pyo DH, Hong H, Lee HO, Park WY, Yang JO, Kim YJ. Shim H, et al. Among authors: hong y, hong h. BMB Rep. 2024 Feb;57(2):110-115. doi: 10.5483/BMBRep.2023-0093. BMB Rep. 2024. PMID: 37605617 Free PMC article.
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