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Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass.
Maupin KA, Himes ER, Plett AP, Chua HL, Singh P, Ghosh J, Mohamad SF, Abeysekera I, Fisher A, Sampson C, Hong JM, Childress P, Alvarez M, Srour EF, Bruzzaniti A, Pelus LM, Orschell CM, Kacena MA. Maupin KA, et al. Among authors: hong jm. Bone. 2019 Oct;127:452-459. doi: 10.1016/j.bone.2019.07.010. Epub 2019 Jul 9. Bone. 2019. PMID: 31299382 Free PMC article.
Megakaryocytes promote osteoclastogenesis in aging.
Kanagasabapathy D, Blosser RJ, Maupin KA, Hong JM, Alvarez M, Ghosh J, Mohamad SF, Aguilar-Perez A, Srour EF, Kacena MA, Bruzzaniti A. Kanagasabapathy D, et al. Among authors: hong jm. Aging (Albany NY). 2020 Jul 7;12(14):15121-15133. doi: 10.18632/aging.103595. Epub 2020 Jul 7. Aging (Albany NY). 2020. PMID: 32634116 Free PMC article.
Osteomacs interact with megakaryocytes and osteoblasts to regulate murine hematopoietic stem cell function.
Mohamad SF, Xu L, Ghosh J, Childress PJ, Abeysekera I, Himes ER, Wu H, Alvarez MB, Davis KM, Aguilar-Perez A, Hong JM, Bruzzaniti A, Kacena MA, Srour EF. Mohamad SF, et al. Among authors: hong jm. Blood Adv. 2017 Dec 5;1(26):2520-2528. doi: 10.1182/bloodadvances.2017011304. eCollection 2017 Dec 12. Blood Adv. 2017. PMID: 29296903 Free PMC article.
The proto-oncogene function of Mdm2 in bone.
Olivos DJ 3rd, Perrien DS, Hooker A, Cheng YH, Fuchs RK, Hong JM, Bruzzaniti A, Chun K, Eischen CM, Kacena MA, Mayo LD. Olivos DJ 3rd, et al. Among authors: hong jm. J Cell Biochem. 2018 Nov;119(11):8830-8840. doi: 10.1002/jcb.27133. Epub 2018 Jul 16. J Cell Biochem. 2018. PMID: 30011084 Free PMC article.
489 results