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Linking the FTO obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo.
Laber S, Forcisi S, Bentley L, Petzold J, Moritz F, Smirnov KS, Al Sadat L, Williamson I, Strobel S, Agnew T, Sengupta S, Nicol T, Grallert H, Heier M, Honecker J, Mianne J, Teboul L, Dumbell R, Long H, Simon M, Lindgren C, Bickmore WA, Hauner H, Schmitt-Kopplin P, Claussnitzer M, Cox RD. Laber S, et al. Among authors: honecker j. Sci Adv. 2021 Jul 21;7(30):eabg0108. doi: 10.1126/sciadv.abg0108. Print 2021 Jul. Sci Adv. 2021. PMID: 34290091 Free PMC article.
Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits.
Glastonbury CA, Pulit SL, Honecker J, Censin JC, Laber S, Yaghootkar H, Rahmioglu N, Pastel E, Kos K, Pitt A, Hudson M, Nellåker C, Beer NL, Hauner H, Becker CM, Zondervan KT, Frayling TM, Claussnitzer M, Lindgren CM. Glastonbury CA, et al. Among authors: honecker j. PLoS Comput Biol. 2020 Aug 14;16(8):e1008044. doi: 10.1371/journal.pcbi.1008044. eCollection 2020 Aug. PLoS Comput Biol. 2020. PMID: 32797044 Free PMC article.
Lipid droplet-size mapping in human adipose tissue using a clinical 3T system.
Weidlich D, Honecker J, Boehm C, Ruschke S, Junker D, Van AT, Makowski MR, Holzapfel C, Claussnitzer M, Hauner H, Karampinos DC. Weidlich D, et al. Among authors: honecker j. Magn Reson Med. 2021 Sep;86(3):1256-1270. doi: 10.1002/mrm.28755. Epub 2021 Apr 1. Magn Reson Med. 2021. PMID: 33797107
Specific miRNAs are associated with human cancer cachexia in an organ-specific manner.
Krauss T, Heisz S, Honecker J, Prokopchuk O, Martignoni M, Janssen KP, Claussnitzer M, Hauner H, Seeliger C. Krauss T, et al. Among authors: honecker j. J Cachexia Sarcopenia Muscle. 2023 Jun;14(3):1381-1394. doi: 10.1002/jcsm.13224. Epub 2023 Apr 6. J Cachexia Sarcopenia Muscle. 2023. PMID: 37021483 Free PMC article.
A non-coding variant linked to metabolic obesity with normal weight affects actin remodelling in subcutaneous adipocytes.
Glunk V, Laber S, Sinnott-Armstrong N, Sobreira DR, Strobel SM, Batista TM, Kubitz P, Moud BN, Ebert H, Huang Y, Brandl B, Garbo G, Honecker J, Stirling DR, Abdennur N, Calabuig-Navarro V, Skurk T, Ocvirk S, Stemmer K, Cimini BA, Carpenter AE, Dankel SN, Lindgren CM, Hauner H, Nobrega MA, Claussnitzer M. Glunk V, et al. Among authors: honecker j. Nat Metab. 2023 May;5(5):861-879. doi: 10.1038/s42255-023-00807-w. Epub 2023 May 30. Nat Metab. 2023. PMID: 37253881
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