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Ultra-high-throughput Ca2+ assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation.
iScience. 2021 Dec 31;25(1):103718. doi: 10.1016/j.isci.2021.103718. eCollection 2022 Jan 21.
iScience. 2021.
PMID: 35072010
Free PMC article.
Hit Discovery for Public Target Programs in the European Lead Factory: Experiences and Output from Assay Development and Ultra-High-Throughput Screening.
Honarnejad S, van Boeckel S, van den Hurk H, van Helden S.
Honarnejad S, et al.
SLAS Discov. 2021 Feb;26(2):192-204. doi: 10.1177/2472555220942765. Epub 2020 Jul 31.
SLAS Discov. 2021.
PMID: 32734803
Free PMC article.
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IMI European Lead Factory - democratizing access to high-throughput screening.
Jones PS, Boucharens S, McElroy SP, Morrison A, Honarnejad S, van Boeckel S, van den Hurk H, Basting D, Hüser J, Jaroch S, Ottow E, Benningshof J, Folmer RHA, Leemhuis F, Kramer-Verhulst PM, Nies VJM, Orrling KM, Rijnders T, Pfander C, Engkvist O, Pairaudeau G, Simpson PB, Ortholand JY, Roche D, Dömling A, Kühnert SM, Roevens PWM, van Vlijmen H, van Wanrooij EJA, Verbruggen C, Nussbaumer P, Ovaa H, van der Stelt M, Simonsen KB, Tagmose L, Waldmann H, Duffy J, Finsinger D, Jurzak M, Burgess-Brown NA, Lee WH, Rutjes FPJT, Haag H, Kallus C, Mors H, Dorval T, Lesur B, Ramon Olayo F, Hamza D, Jones G, Pearce C, Piechot A, Tzalis D, Clausen MH, Davis J, Derouane D, Vermeiren C, Kaiser M, Stockman RA, Barrault DV, Pannifer AD, Swedlow JR, Nelson AS, Orru RVA, Ruijter E, van Helden SP, Li VM, Vries T, de Vlieger JSB.
Jones PS, et al. Among authors: honarnejad s.
Nat Rev Drug Discov. 2022 Apr;21(4):245-246. doi: 10.1038/d41573-021-00196-3.
Nat Rev Drug Discov. 2022.
PMID: 34907316
No abstract available.
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Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a nano luciferase reporter read-out.
Dechering KJ, Timmerman M, Rensen K, Koolen KMJ, Honarnejad S, Vos MW, Huijs T, Henderson RWM, Chenu E, Laleu B, Montefiore BC, Segall MD, Mills JEJ, Guantai EM, Duffy J, Duffey M.
Dechering KJ, et al. Among authors: honarnejad s.
SLAS Discov. 2022 Sep;27(6):337-348. doi: 10.1016/j.slasd.2022.07.002. Epub 2022 Jul 21.
SLAS Discov. 2022.
PMID: 35872229
Free article.
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The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds.
Gising J, Honarnejad S, Bras M, Baillie GL, McElroy SP, Jones PS, Morrison A, Beveridge J, Hallberg M, Larhed M.
Gising J, et al. Among authors: honarnejad s.
Int J Mol Sci. 2024 Apr 6;25(7):4084. doi: 10.3390/ijms25074084.
Int J Mol Sci. 2024.
PMID: 38612894
Free PMC article.
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Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics.
Fernández DI, Troitiño S, Sobota V, Tullemans BME, Zou J, van den Hurk H, García Á, Honarnejad S, Kuijpers MJE, Heemskerk JWM.
Fernández DI, et al. Among authors: honarnejad s.
Sci Rep. 2024 Mar 14;14(1):6229. doi: 10.1038/s41598-024-56799-4.
Sci Rep. 2024.
PMID: 38486006
Free PMC article.
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Metrics other than potency reveal systematic variation in responses to cancer drugs.
Fallahi-Sichani M, Honarnejad S, Heiser LM, Gray JW, Sorger PK.
Fallahi-Sichani M, et al. Among authors: honarnejad s.
Nat Chem Biol. 2013 Nov;9(11):708-14. doi: 10.1038/nchembio.1337. Epub 2013 Sep 8.
Nat Chem Biol. 2013.
PMID: 24013279
Free PMC article.
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