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Adhesion-mediated mechanosignaling forces mitohormesis.
Tharp KM, Higuchi-Sanabria R, Timblin GA, Ford B, Garzon-Coral C, Schneider C, Muncie JM, Stashko C, Daniele JR, Moore AS, Frankino PA, Homentcovschi S, Manoli SS, Shao H, Richards AL, Chen KH, Hoeve JT, Ku GM, Hellerstein M, Nomura DK, Saijo K, Gestwicki J, Dunn AR, Krogan NJ, Swaney DL, Dillin A, Weaver VM. Tharp KM, et al. Among authors: homentcovschi s. Cell Metab. 2021 Jul 6;33(7):1322-1341.e13. doi: 10.1016/j.cmet.2021.04.017. Epub 2021 May 20. Cell Metab. 2021. PMID: 34019840 Free PMC article.
Divergent Nodes of Non-autonomous UPRER Signaling through Serotonergic and Dopaminergic Neurons.
Higuchi-Sanabria R, Durieux J, Kelet N, Homentcovschi S, de Los Rios Rogers M, Monshietehadi S, Garcia G, Dallarda S, Daniele JR, Ramachandran V, Sahay A, Tronnes SU, Joe L, Dillin A. Higuchi-Sanabria R, et al. Among authors: homentcovschi s. Cell Rep. 2020 Dec 8;33(10):108489. doi: 10.1016/j.celrep.2020.108489. Cell Rep. 2020. PMID: 33296657 Free PMC article.
Cross-species screening platforms identify EPS-8 as a critical link for mitochondrial stress and actin stabilization.
Moehle EA, Higuchi-Sanabria R, Tsui CK, Homentcovschi S, Tharp KM, Zhang H, Chi H, Joe L, de Los Rios Rogers M, Sahay A, Kelet N, Benitez C, Bar-Ziv R, Garcia G, Shen K, Frankino PA, Schinzel RT, Shalem O, Dillin A. Moehle EA, et al. Among authors: homentcovschi s. Sci Adv. 2021 Oct 29;7(44):eabj6818. doi: 10.1126/sciadv.abj6818. Epub 2021 Oct 29. Sci Adv. 2021. PMID: 34714674 Free PMC article.
Lysosomal recycling of amino acids affects ER quality control.
Higuchi-Sanabria R, Shen K, Kelet N, Frankino PA, Durieux J, Bar-Ziv R, Sing CN, Garcia EJ, Homentcovschi S, Sanchez M, Wu R, Tronnes SU, Joe L, Webster B, Ahilon-Jeronimo A, Monshietehadi S, Dallarda S, Pender C, Pon LA, Zoncu R, Dillin A. Higuchi-Sanabria R, et al. Among authors: homentcovschi s. Sci Adv. 2020 Jun 26;6(26):eaaz9805. doi: 10.1126/sciadv.aaz9805. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32637599 Free PMC article.