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A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice.
Barendrecht S, Schreurs A, Geissler S, Sabanov V, Ilse V, Rieckmann V, Eichentopf R, Künemund A, Hietel B, Wussow S, Hoffmann K, Körber-Ferl K, Pandey R, Carter GW, Demuth HU, Holzer M, Roßner S, Schilling S, Preuss C, Balschun D, Cynis H. Barendrecht S, et al. Among authors: holzer m. Alzheimers Res Ther. 2023 Jan 14;15(1):16. doi: 10.1186/s13195-022-01144-y. Alzheimers Res Ther. 2023. PMID: 36641439 Free PMC article.
Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathology.
Schilling S, Zeitschel U, Hoffmann T, Heiser U, Francke M, Kehlen A, Holzer M, Hutter-Paier B, Prokesch M, Windisch M, Jagla W, Schlenzig D, Lindner C, Rudolph T, Reuter G, Cynis H, Montag D, Demuth HU, Rossner S. Schilling S, et al. Among authors: holzer m. Nat Med. 2008 Oct;14(10):1106-11. doi: 10.1038/nm.1872. Epub 2008 Sep 28. Nat Med. 2008. PMID: 18836460
A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies.
Hartlage-Rübsamen M, Bluhm A, Moceri S, Machner L, Köppen J, Schenk M, Hilbrich I, Holzer M, Weidenfeller M, Richter F, Coras R, Serrano GE, Beach TG, Schilling S, von Hörsten S, Xiang W, Schulze A, Roßner S. Hartlage-Rübsamen M, et al. Among authors: holzer m. Acta Neuropathol. 2021 Sep;142(3):399-421. doi: 10.1007/s00401-021-02349-5. Epub 2021 Jul 26. Acta Neuropathol. 2021. PMID: 34309760 Free PMC article.
Tau and tauopathies.
Arendt T, Stieler JT, Holzer M. Arendt T, et al. Among authors: holzer m. Brain Res Bull. 2016 Sep;126(Pt 3):238-292. doi: 10.1016/j.brainresbull.2016.08.018. Epub 2016 Sep 9. Brain Res Bull. 2016. PMID: 27615390 Review.
585 results