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A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk.
Chang D, Hunkapiller J, Bhangale T, Reeder J, Mukhyala K, Tom J, Cowgill A, Vogel J, Forrest WF, Khan Z, Stockwell A, McCarthy MI, Staton TL, Olsson J, Holweg CTJ, Cheung DS, Chen H, Brauer MJ, Graham RR, Behrens T, Wilson MS, Arron JR, Choy DF, Yaspan BL. Chang D, et al. Among authors: holweg ctj. Sci Rep. 2022 Apr 2;12(1):5574. doi: 10.1038/s41598-022-09447-8. Sci Rep. 2022. PMID: 35368043 Free PMC article.
Interleukin-13 in Asthma and Other Eosinophilic Disorders.
Doran E, Cai F, Holweg CTJ, Wong K, Brumm J, Arron JR. Doran E, et al. Among authors: holweg ctj. Front Med (Lausanne). 2017 Sep 19;4:139. doi: 10.3389/fmed.2017.00139. eCollection 2017. Front Med (Lausanne). 2017. PMID: 29034234 Free PMC article.
Exacerbation Profile and Risk Factors in a Type-2-Low Enriched Severe Asthma Cohort: A Clinical Trial to Assess Asthma Exacerbation Phenotypes.
McDowell PJ, Busby J, Hanratty CE, Djukanovic R, Woodcock A, Walker S, Hardman TC, Arron JR, Choy DF, Bradding P, Brightling CE, Chaudhuri R, Cowan D, Mansur AH, Fowler SJ, Diver SE, Howarth P, Lordan J, Menzies-Gow A, Harrison T, Robinson DS, Holweg CTJ, Matthews JG, Pavord ID, Heaney LG. McDowell PJ, et al. Among authors: holweg ctj. Am J Respir Crit Care Med. 2022 Sep 1;206(5):545-553. doi: 10.1164/rccm.202201-0129OC. Am J Respir Crit Care Med. 2022. PMID: 35549845 Free PMC article. Clinical Trial.
A randomized, placebo-controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER).
Austin CD, Gonzalez Edick M, Ferrando RE, Solon M, Baca M, Mesh K, Bradding P, Gauvreau GM, Sumino K, FitzGerald JM, Israel E, Bjermer L, Bourdin A, Arron JR, Choy DF, Olsson JK, Abreu F, Howard M, Wong K, Cai F, Peng K, Putnam WS, Holweg CTJ, Matthews JG, Kraft M, Woodruff PG; CLAVIER Investigators. Austin CD, et al. Among authors: holweg ctj. Clin Exp Allergy. 2020 Dec;50(12):1342-1351. doi: 10.1111/cea.13731. Epub 2020 Oct 4. Clin Exp Allergy. 2020. PMID: 32909660 Free PMC article. Clinical Trial.
Factors affecting adherence with treatment advice in a clinical trial of patients with severe asthma.
Busby J, Matthews JG, Chaudhuri R, Pavord ID, Hardman TC, Arron JR, Bradding P, Brightling CE, Choy DF, Cowan DC, Djukanovic R, Hanratty CE, Harrison TW, Holweg CT, Howarth PH, Fowler SJ, Lordan JL, Mansur AH, Menzies-Gow A, Niven RM, Robinson DS, Walker SM, Woodcock A, Heaney LG; investigators for the MRC Refractory Asthma Stratification Programme. Busby J, et al. Eur Respir J. 2021 Sep 24;59(4):2100768. doi: 10.1183/13993003.00768-2021. Print 2022 Apr. Eur Respir J. 2021. PMID: 34561291 Free PMC article. Clinical Trial.
Model-based clinical pharmacology profiling and exposure-response relationships of the efficacy and biomarker of lebrikizumab in patients with moderate-to-severe asthma.
Zhu R, Zheng Y, Dirks NL, Vadhavkar S, Jin JY, Peng K, Holweg CTJ, Olsson J, Matthews JG, Putnam WS. Zhu R, et al. Among authors: holweg ctj. Pulm Pharmacol Ther. 2017 Oct;46:88-98. doi: 10.1016/j.pupt.2017.08.010. Epub 2017 Aug 24. Pulm Pharmacol Ther. 2017. PMID: 28843617 Free article.
Roles of Periostin in Respiratory Disorders.
Izuhara K, Conway SJ, Moore BB, Matsumoto H, Holweg CT, Matthews JG, Arron JR. Izuhara K, et al. Am J Respir Crit Care Med. 2016 May 1;193(9):949-56. doi: 10.1164/rccm.201510-2032PP. Am J Respir Crit Care Med. 2016. PMID: 26756066 Free PMC article. Review.
87 results