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Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial.
Trøseid M, Arribas JR, Assoumou L, Holten AR, Poissy J, Terzić V, Mazzaferri F, Baño JR, Eustace J, Hites M, Joannidis M, Paiva JA, Reuter J, Püntmann I, Patrick-Brown TDJH, Westerheim E, Nezvalova-Henriksen K, Beniguel L, Dahl TB, Bouscambert M, Halanova M, Péterfi Z, Tsiodras S, Rezek M, Briel M, Ünal S, Schlegel M, Ader F, Lacombe K, Amdal CD, Rodrigues S, Tonby K, Gaudet A, Heggelund L, Mootien J, Johannessen A, Møller JH, Pollan BD, Tveita AA, Kildal AB, Richard JC, Dalgard O, Simensen VC, Baldé A, de Gastines L, Del Álamo M, Aydin B, Lund-Johansen F, Trabaud MA, Diallo A, Halvorsen B, Røttingen JA, Tacconelli E, Yazdanpanah Y, Olsen IC, Costagliola D; EU SolidAct study group. Trøseid M, et al. Among authors: holten ar. Crit Care. 2023 Jan 10;27(1):9. doi: 10.1186/s13054-022-04205-8. Crit Care. 2023. PMID: 36627655 Free PMC article. Clinical Trial.
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients.
Holter JC, Pischke SE, de Boer E, Lind A, Jenum S, Holten AR, Tonby K, Barratt-Due A, Sokolova M, Schjalm C, Chaban V, Kolderup A, Tran T, Tollefsrud Gjølberg T, Skeie LG, Hesstvedt L, Ormåsen V, Fevang B, Austad C, Müller KE, Fladeby C, Holberg-Petersen M, Halvorsen B, Müller F, Aukrust P, Dudman S, Ueland T, Andersen JT, Lund-Johansen F, Heggelund L, Dyrhol-Riise AM, Mollnes TE. Holter JC, et al. Among authors: holten ar. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):25018-25025. doi: 10.1073/pnas.2010540117. Epub 2020 Sep 17. Proc Natl Acad Sci U S A. 2020. PMID: 32943538 Free PMC article.
Elevated plasma sTIM-3 levels in patients with severe COVID-19.
Ueland T, Heggelund L, Lind A, Holten AR, Tonby K, Michelsen AE, Jenum S, Jørgensen MJ, Barratt-Due A, Skeie LG, Nordøy I, Aanensen Fraz MS, Quist-Paulsen E E, Pischke SE, Johal SK, Hesstvedt L, Bogen M, Fevang B, Halvorsen B, Müller F, Bekken GK, Mollnes TE, Dudman S, Aukrust P, Dyrhol-Riise AM, Holter JC. Ueland T, et al. Among authors: holten ar. J Allergy Clin Immunol. 2021 Jan;147(1):92-98. doi: 10.1016/j.jaci.2020.09.007. Epub 2020 Sep 21. J Allergy Clin Immunol. 2021. PMID: 32971109 Free PMC article. Clinical Trial.
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.
WHO Solidarity Trial Consortium; Pan H, Peto R, Henao-Restrepo AM, Preziosi MP, Sathiyamoorthy V, Abdool Karim Q, Alejandria MM, Hernández García C, Kieny MP, Malekzadeh R, Murthy S, Reddy KS, Roses Periago M, Abi Hanna P, Ader F, Al-Bader AM, Alhasawi A, Allum E, Alotaibi A, Alvarez-Moreno CA, Appadoo S, Asiri A, Aukrust P, Barratt-Due A, Bellani S, Branca M, Cappel-Porter HBC, Cerrato N, Chow TS, Como N, Eustace J, García PJ, Godbole S, Gotuzzo E, Griskevicius L, Hamra R, Hassan M, Hassany M, Hutton D, Irmansyah I, Jancoriene L, Kirwan J, Kumar S, Lennon P, Lopardo G, Lydon P, Magrini N, Maguire T, Manevska S, Manuel O, McGinty S, Medina MT, Mesa Rubio ML, Miranda-Montoya MC, Nel J, Nunes EP, Perola M, Portolés A, Rasmin MR, Raza A, Rees H, Reges PPS, Rogers CA, Salami K, Salvadori MI, Sinani N, Sterne JAC, Stevanovikj M, Tacconelli E, Tikkinen KAO, Trelle S, Zaid H, Røttingen JA, Swaminathan S. WHO Solidarity Trial Consortium, et al. N Engl J Med. 2021 Feb 11;384(6):497-511. doi: 10.1056/NEJMoa2023184. Epub 2020 Dec 2. N Engl J Med. 2021. PMID: 33264556 Free PMC article. Clinical Trial.
Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19.
Jøntvedt Jørgensen M, Holter JC, Christensen EE, Schjalm C, Tonby K, Pischke SE, Jenum S, Skeie LG, Nur S, Lind A, Opsand H, Enersen TB, Grøndahl R, Hermann A, Dudman S, Muller F, Ueland T, Mollnes TE, Aukrust P, Heggelund L, Holten AR, Dyrhol-Riise AM. Jøntvedt Jørgensen M, et al. Among authors: holten ar. Sci Rep. 2020 Dec 10;10(1):21697. doi: 10.1038/s41598-020-78710-7. Sci Rep. 2020. PMID: 33303843 Free PMC article. Clinical Trial.
Serum ACE as a prognostic biomarker in COVID-19: a case series.
Kolberg ES, Wickstrøm K, Tonby K, Dyrhol-Riise AM, Holten AR, Amundsen EK. Kolberg ES, et al. Among authors: holten ar. APMIS. 2021 Apr;129(4):237-238. doi: 10.1111/apm.13108. Epub 2021 Jan 15. APMIS. 2021. PMID: 33368687 No abstract available.
Predicting severe COVID-19 in the Emergency Department.
Holten AR, Nore KG, Tveiten CEVWK, Olasveengen TM, Tonby K. Holten AR, et al. Resusc Plus. 2020 Dec;4:100042. doi: 10.1016/j.resplu.2020.100042. Epub 2020 Oct 21. Resusc Plus. 2020. PMID: 33403367 Free PMC article.
Increased inflammatory markers reflecting fibrogenesis are independently associated with cardiac involvement in hospitalized COVID-19 patients.
Ueland T, Dyrhol-Riise AM, Woll BM, Holten AR, Petteresen F, Lind A, Dudman SG, Heggelund L, Holter JC, Aukrust P. Ueland T, et al. Among authors: holten ar. J Infect. 2021 May;82(5):186-230. doi: 10.1016/j.jinf.2021.01.017. Epub 2021 Jan 28. J Infect. 2021. PMID: 33516748 Free PMC article. No abstract available.
Delirium is common in patients hospitalized with COVID-19.
Watne LO, Tonby K, Holten AR, Olasveengen TM, Romundstad LG, Neerland BE. Watne LO, et al. Among authors: holten ar. Intern Emerg Med. 2021 Oct;16(7):1997-2000. doi: 10.1007/s11739-021-02715-x. Epub 2021 Apr 8. Intern Emerg Med. 2021. PMID: 33830418 Free PMC article. No abstract available.
50 results