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Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels.
Giese APJ, Weng WH, Kindt KS, Chang HHV, Montgomery JS, Ratzan EM, Beirl AJ, Rivera RA, Lotthammer JM, Walujkar S, Foster MP, Zobeiri OA, Holt JR, Riazuddin S, Cullen KE, Sotomayor M, Ahmed ZM. Giese APJ, et al. Among authors: holt jr. bioRxiv [Preprint]. 2023 May 30:2023.05.26.542533. doi: 10.1101/2023.05.26.542533. bioRxiv. 2023. PMID: 37398045 Free PMC article. Preprint.
Molecular earplugs to protect the inner ear.
Chaves MG, Holt JR. Chaves MG, et al. Among authors: holt jr. Mol Ther Methods Clin Dev. 2023 Apr 26;29:284-285. doi: 10.1016/j.omtm.2023.04.001. eCollection 2023 Jun 8. Mol Ther Methods Clin Dev. 2023. PMID: 37168274 Free PMC article. No abstract available.
TMC function, dysfunction, and restoration in mouse vestibular organs.
Ratzan EM, Lee J, Madison MA, Zhu H, Zhou W, Géléoc GSG, Holt JR. Ratzan EM, et al. Among authors: holt jr. Front Neurol. 2024 Apr 4;15:1356614. doi: 10.3389/fneur.2024.1356614. eCollection 2024. Front Neurol. 2024. PMID: 38638308 Free PMC article.
FXR Agonism with Bile Acid Mimetic Reduces Pre-Clinical Triple-Negative Breast Cancer Burden.
Joseph SC, Eugin Simon S, Bohm MS, Kim M, Pye ME, Simmons BW, Graves DG, Thomas-Gooch SM, Tanveer UA, Holt JR, Ponnusamy S, Sipe LM, Hayes DN, Cook KL, Narayanan R, Pierre JF, Makowski L. Joseph SC, et al. Among authors: holt jr. Cancers (Basel). 2024 Mar 30;16(7):1368. doi: 10.3390/cancers16071368. Cancers (Basel). 2024. PMID: 38611046 Free PMC article.
PIEZO1-HaloTag hiPSCs: Bridging Molecular, Cellular and Tissue Imaging.
Bertaccini GA, Evans EL, Nourse JL, Dickinson GD, Liu G, Casanellas I, Seal S, Ly AT, Holt JR, Yan S, Hui EE, Panicker MM, Upadhyayula S, Parker I, Pathak MM. Bertaccini GA, et al. Among authors: holt jr. bioRxiv [Preprint]. 2023 Dec 23:2023.12.22.573117. doi: 10.1101/2023.12.22.573117. bioRxiv. 2023. PMID: 38187535 Free PMC article. Preprint.
Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer.
Chaib M, Holt JR, Fisher EL, Sipe LM, Bohm MS, Joseph SC, Simmons BW, Eugin Simon S, Yarbro JR, Tanveer U, Halle JL, Carson JA, Hollingsworth TJ, Wei Q, Rathmell JC, Thomas PG, Hayes DN, Makowski L. Chaib M, et al. Among authors: holt jr. Sci Adv. 2023 Dec 22;9(51):eadd3231. doi: 10.1126/sciadv.add3231. Epub 2023 Dec 22. Sci Adv. 2023. PMID: 38134280 Free PMC article.
322 results