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Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice.
Mathiesen BK, Miyakoshi LM, Cederroth CR, Tserga E, Versteegh C, Bork PAR, Hauglund NL, Gomolka RS, Mori Y, Edvall NK, Rouse S, Møllgård K, Holt JR, Nedergaard M, Canlon B. Mathiesen BK, et al. Among authors: holt jr. Sci Transl Med. 2023 Jun 28;15(702):eabq3916. doi: 10.1126/scitranslmed.abq3916. Epub 2023 Jun 28. Sci Transl Med. 2023. PMID: 37379370
Tmc gene therapy restores auditory function in deaf mice.
Askew C, Rochat C, Pan B, Asai Y, Ahmed H, Child E, Schneider BL, Aebischer P, Holt JR. Askew C, et al. Among authors: holt jr. Sci Transl Med. 2015 Jul 8;7(295):295ra108. doi: 10.1126/scitranslmed.aab1996. Sci Transl Med. 2015. PMID: 26157030 Free PMC article.
Sound strategies for hearing restoration.
Géléoc GS, Holt JR. Géléoc GS, et al. Among authors: holt jr. Science. 2014 May 9;344(6184):1241062. doi: 10.1126/science.1241062. Science. 2014. PMID: 24812404 Free PMC article. Review.
Emerging Gene Therapies for Genetic Hearing Loss.
Ahmed H, Shubina-Oleinik O, Holt JR. Ahmed H, et al. Among authors: holt jr. J Assoc Res Otolaryngol. 2017 Oct;18(5):649-670. doi: 10.1007/s10162-017-0634-8. Epub 2017 Aug 16. J Assoc Res Otolaryngol. 2017. PMID: 28815315 Free PMC article. Review.
Split otoferlins reunited.
Holt JR, Geleoc GS. Holt JR, et al. EMBO Mol Med. 2019 Jan;11(1):e9995. doi: 10.15252/emmm.201809995. EMBO Mol Med. 2019. PMID: 30573543 Free PMC article.
322 results