Holt JR - Search Results

1

Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing.

Atcha H, Jairaman A, Holt JR, Meli VS, Nagalla RR, Veerasubramanian PK, Brumm KT, Lim HE, Othy S, Cahalan MD, Pathak MM, Liu WF. Atcha H, et al. Among authors: holt jr. Nat Commun. 2021 May 31;12(1):3256. doi: 10.1038/s41467-021-23482-5. Nat Commun. 2021. PMID: 34059671 Free PMC article.

2

Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca²⁺ flickers.

Ellefsen KL, Holt JR, Chang AC, Nourse JL, Arulmoli J, Mekhdjian AH, Abuwarda H, Tombola F, Flanagan LA, Dunn AR, Parker I, Pathak MM. Ellefsen KL, et al. Among authors: holt jr. Commun Biol. 2019 Aug 7;2:298. doi: 10.1038/s42003-019-0514-3. eCollection 2019. Commun Biol. 2019. PMID: 31396578 Free PMC article.

3

Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4⁺ T cell responses.

Jairaman A, Othy S, Dynes JL, Yeromin AV, Zavala A, Greenberg ML, Nourse JL, Holt JR, Cahalan SM, Marangoni F, Parker I, Pathak MM, Cahalan MD. Jairaman A, et al. Among authors: holt jr. Sci Adv. 2021 Jul 7;7(28):eabg5859. doi: 10.1126/sciadv.abg5859. Print 2021 Jul. Sci Adv. 2021. PMID: 34233878 Free PMC article.

4

Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing.

Holt JR, Zeng WZ, Evans EL, Woo SH, Ma S, Abuwarda H, Loud M, Patapoutian A, Pathak MM. Holt JR, et al. Elife. 2021 Sep 27;10:e65415. doi: 10.7554/eLife.65415. Elife. 2021. PMID: 34569935 Free PMC article.

5

PIEZO1-HaloTag hiPSCs: Bridging Molecular, Cellular and Tissue Imaging.

Bertaccini GA, Evans EL, Nourse JL, Dickinson GD, Liu G, Casanellas I, Seal S, Ly AT, Holt JR, Yan S, Hui EE, Panicker MM, Upadhyayula S, Parker I, Pathak MM. Bertaccini GA, et al. Among authors: holt jr. bioRxiv [Preprint]. 2023 Dec 23:2023.12.22.573117. doi: 10.1101/2023.12.22.573117. bioRxiv. 2023. PMID: 38187535 Free PMC article. Preprint.

6

PIEZO1 regulates leader cell formation and cellular coordination during collective keratinocyte migration.

Chen J, Holt JR, Evans EL, Lowengrub JS, Pathak MM. Chen J, et al. Among authors: holt jr. PLoS Comput Biol. 2024 Apr 5;20(4):e1011855. doi: 10.1371/journal.pcbi.1011855. eCollection 2024 Apr. PLoS Comput Biol. 2024. PMID: 38578817 Free PMC article.

7

Correction: Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing.

Holt JR, Zeng WZ, Evans EL, Woo SH, Ma S, Abuwarda H, Loud M, Patapoutian A, Pathak MM. Holt JR, et al. Elife. 2022 Apr 1;11:e79034. doi: 10.7554/eLife.79034. Elife. 2022. PMID: 35362412 Free PMC article.

8

Sensory transduction in auditory hair cells-PIEZOs can't touch this.

Holt JR, Fettiplace R, Müller U. Holt JR, et al. J Gen Physiol. 2024 Jun 3;156(6):e202413585. doi: 10.1085/jgp.202413585. Epub 2024 May 10. J Gen Physiol. 2024. PMID: 38727631 Free article. No abstract available.

9

TMC function, dysfunction, and restoration in mouse vestibular organs.

Ratzan EM, Lee J, Madison MA, Zhu H, Zhou W, Géléoc GSG, Holt JR. Ratzan EM, et al. Among authors: holt jr. Front Neurol. 2024 Apr 4;15:1356614. doi: 10.3389/fneur.2024.1356614. eCollection 2024. Front Neurol. 2024. PMID: 38638308 Free PMC article.

10

FXR Agonism with Bile Acid Mimetic Reduces Pre-Clinical Triple-Negative Breast Cancer Burden.

Joseph SC, Eugin Simon S, Bohm MS, Kim M, Pye ME, Simmons BW, Graves DG, Thomas-Gooch SM, Tanveer UA, Holt JR, Ponnusamy S, Sipe LM, Hayes DN, Cook KL, Narayanan R, Pierre JF, Makowski L. Joseph SC, et al. Among authors: holt jr. Cancers (Basel). 2024 Mar 30;16(7):1368. doi: 10.3390/cancers16071368. Cancers (Basel). 2024. PMID: 38611046 Free PMC article.

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