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Chromatin biology: Breaking into the PRC2 cage.
Holoch D, Margueron R. Holoch D, et al. Nat Chem Biol. 2017 Apr;13(4):345-346. doi: 10.1038/nchembio.2313. Epub 2017 Jan 30. Nat Chem Biol. 2017. PMID: 28135238 No abstract available.
A meiotic XPF-ERCC1-like complex recognizes joint molecule recombination intermediates to promote crossover formation.
De Muyt A, Pyatnitskaya A, Andréani J, Ranjha L, Ramus C, Laureau R, Fernandez-Vega A, Holoch D, Girard E, Govin J, Margueron R, Couté Y, Cejka P, Guérois R, Borde V. De Muyt A, et al. Among authors: holoch d. Genes Dev. 2018 Feb 1;32(3-4):283-296. doi: 10.1101/gad.308510.117. Epub 2018 Feb 9. Genes Dev. 2018. PMID: 29440262 Free PMC article.
A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.
Conway E, Jerman E, Healy E, Ito S, Holoch D, Oliviero G, Deevy O, Glancy E, Fitzpatrick DJ, Mucha M, Watson A, Rice AM, Chammas P, Huang C, Pratt-Kelly I, Koseki Y, Nakayama M, Ishikura T, Streubel G, Wynne K, Hokamp K, McLysaght A, Ciferri C, Di Croce L, Cagney G, Margueron R, Koseki H, Bracken AP. Conway E, et al. Among authors: holoch d. Mol Cell. 2018 May 3;70(3):408-421.e8. doi: 10.1016/j.molcel.2018.03.005. Epub 2018 Apr 5. Mol Cell. 2018. PMID: 29628311 Free article.
Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements.
Miró-Pina C, Charmant O, Kawaguchi T, Holoch D, Michaud A, Cohen I, Humbert A, Jaszczyszyn Y, Chevreux G, Del Maestro L, Ait-Si-Ali S, Arnaiz O, Margueron R, Duharcourt S. Miró-Pina C, et al. Among authors: holoch d. Dev Cell. 2022 Apr 25;57(8):1037-1052.e8. doi: 10.1016/j.devcel.2022.03.014. Epub 2022 Apr 15. Dev Cell. 2022. PMID: 35429435 Free article.
Automated CUT & RUN Using the KingFisher Duo Prime.
Aflaki S, Margueron R, Holoch D. Aflaki S, et al. Among authors: holoch d. Methods Mol Biol. 2022;2529:253-265. doi: 10.1007/978-1-0716-2481-4_12. Methods Mol Biol. 2022. PMID: 35733019
EZH2 mutations in follicular lymphoma distort H3K27me3 profiles and alter transcriptional responses to PRC2 inhibition.
Romero P, Richart L, Aflaki S, Petitalot A, Burton M, Michaud A, Masliah-Planchon J, Kuhnowski F, Le Cam S, Baliñas-Gavira C, Méaudre C, Luscan A, Hamza A, Legoix P, Vincent-Salomon A, Wassef M, Holoch D, Margueron R. Romero P, et al. Among authors: holoch d. Nat Commun. 2024 Apr 24;15(1):3452. doi: 10.1038/s41467-024-47701-x. Nat Commun. 2024. PMID: 38658543 Free PMC article.
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