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Therapeutic antibodies targeting angiomotin inhibit angiogenesis in vivo.
Levchenko T, Veitonmäki N, Lundkvist A, Gerhardt H, Ming Y, Berggren K, Kvanta A, Carlsson R, Holmgren L. Levchenko T, et al. Among authors: holmgren l. FASEB J. 2008 Mar;22(3):880-9. doi: 10.1096/fj.07-9509com. Epub 2007 Nov 5. FASEB J. 2008. PMID: 17984175
p130-angiomotin associates to actin and controls endothelial cell shape.
Ernkvist M, Aase K, Ukomadu C, Wohlschlegel J, Blackman R, Veitonmäki N, Bratt A, Dutta A, Holmgren L. Ernkvist M, et al. Among authors: holmgren l. FEBS J. 2006 May;273(9):2000-11. doi: 10.1111/j.1742-4658.2006.05216.x. FEBS J. 2006. PMID: 16640563 Free article.
Angiomotin regulates endothelial cell migration during embryonic angiogenesis.
Aase K, Ernkvist M, Ebarasi L, Jakobsson L, Majumdar A, Yi C, Birot O, Ming Y, Kvanta A, Edholm D, Aspenström P, Kissil J, Claesson-Welsh L, Shimono A, Holmgren L. Aase K, et al. Among authors: holmgren l. Genes Dev. 2007 Aug 15;21(16):2055-68. doi: 10.1101/gad.432007. Genes Dev. 2007. PMID: 17699752 Free PMC article.
A DNA vaccine targeting angiomotin inhibits angiogenesis and suppresses tumor growth.
Holmgren L, Ambrosino E, Birot O, Tullus C, Veitonmäki N, Levchenko T, Carlson LM, Musiani P, Iezzi M, Curcio C, Forni G, Cavallo F, Kiessling R. Holmgren L, et al. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9208-13. doi: 10.1073/pnas.0603110103. Epub 2006 Jun 5. Proc Natl Acad Sci U S A. 2006. PMID: 16754857 Free PMC article.
115 results