Holmgren A - Search Results

1

Thioredoxin 1 modulates apoptosis induced by bioactive compounds in prostate cancer cells.

Rodriguez-Garcia A, Hevia D, Mayo JC, Gonzalez-Menendez P, Coppo L, Lu J, Holmgren A, Sainz RM. Rodriguez-Garcia A, et al. Among authors: holmgren a. Redox Biol. 2017 Aug;12:634-647. doi: 10.1016/j.redox.2017.03.025. Epub 2017 Mar 31. Redox Biol. 2017. PMID: 28391184 Free PMC article.

2

Thioredoxin system in cell death progression.

Lu J, Holmgren A. Lu J, et al. Among authors: holmgren a. Antioxid Redox Signal. 2012 Dec 15;17(12):1738-47. doi: 10.1089/ars.2012.4650. Epub 2012 Jun 11. Antioxid Redox Signal. 2012. PMID: 22530689 Review.

3

Glutaredoxin 2 reduces both thioredoxin 2 and thioredoxin 1 and protects cells from apoptosis induced by auranofin and 4-hydroxynonenal.

Zhang H, Du Y, Zhang X, Lu J, Holmgren A. Zhang H, et al. Among authors: holmgren a. Antioxid Redox Signal. 2014 Aug 10;21(5):669-81. doi: 10.1089/ars.2013.5499. Epub 2014 Feb 4. Antioxid Redox Signal. 2014. PMID: 24295294 Free PMC article.

4

Impaired cross-talk between the thioredoxin and glutathione systems is related to ASK-1 mediated apoptosis in neuronal cells exposed to mercury.

Branco V, Coppo L, Solá S, Lu J, Rodrigues CMP, Holmgren A, Carvalho C. Branco V, et al. Among authors: holmgren a. Redox Biol. 2017 Oct;13:278-287. doi: 10.1016/j.redox.2017.05.024. Epub 2017 Jun 1. Redox Biol. 2017. PMID: 28600984 Free PMC article.

5

Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide.

Lu J, Chew EH, Holmgren A. Lu J, et al. Among authors: holmgren a. Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12288-93. doi: 10.1073/pnas.0701549104. Epub 2007 Jul 18. Proc Natl Acad Sci U S A. 2007. PMID: 17640917 Free PMC article.

6

Thioredoxin and thioredoxin reductase: current research with special reference to human disease.

Holmgren A, Lu J. Holmgren A, et al. Biochem Biophys Res Commun. 2010 May 21;396(1):120-4. doi: 10.1016/j.bbrc.2010.03.083. Biochem Biophys Res Commun. 2010. PMID: 20494123 Review.

7

Glutathione and glutaredoxin act as a backup of human thioredoxin reductase 1 to reduce thioredoxin 1 preventing cell death by aurothioglucose.

Du Y, Zhang H, Lu J, Holmgren A. Du Y, et al. Among authors: holmgren a. J Biol Chem. 2012 Nov 2;287(45):38210-9. doi: 10.1074/jbc.M112.392225. Epub 2012 Sep 13. J Biol Chem. 2012. PMID: 22977247 Free PMC article.

8

The thioredoxin antioxidant system.

Lu J, Holmgren A. Lu J, et al. Among authors: holmgren a. Free Radic Biol Med. 2014 Jan;66:75-87. doi: 10.1016/j.freeradbiomed.2013.07.036. Epub 2013 Jul 27. Free Radic Biol Med. 2014. PMID: 23899494 Review.

9

The thioredoxin superfamily in oxidative protein folding.

Lu J, Holmgren A. Lu J, et al. Among authors: holmgren a. Antioxid Redox Signal. 2014 Jul 20;21(3):457-70. doi: 10.1089/ars.2014.5849. Epub 2014 Mar 6. Antioxid Redox Signal. 2014. PMID: 24483600 Review.

10

Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246.

Haffo L, Lu J, Bykov VJN, Martin SS, Ren X, Coppo L, Wiman KG, Holmgren A. Haffo L, et al. Among authors: holmgren a. Sci Rep. 2018 Aug 23;8(1):12671. doi: 10.1038/s41598-018-31048-7. Sci Rep. 2018. PMID: 30140002 Free PMC article.

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