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Can acute dermal systemic toxicity tests be replaced with oral tests? A comparison of route-specific systemic toxicity and hazard classifications under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).
Moore NP, Andrew DJ, Bjerke DL, Creton S, Dreher D, Holmes T, Prieto P, Seidle T, Rowan TG. Moore NP, et al. Among authors: holmes t. Regul Toxicol Pharmacol. 2013 Jun;66(1):30-7. doi: 10.1016/j.yrtph.2013.02.005. Epub 2013 Feb 24. Regul Toxicol Pharmacol. 2013. PMID: 23461858
A global initiative to refine acute inhalation studies through the use of 'evident toxicity' as an endpoint: Towards adoption of the fixed concentration procedure.
Sewell F, Ragan I, Marczylo T, Anderson B, Braun A, Casey W, Dennison N, Griffiths D, Guest R, Holmes T, van Huygevoort T, Indans I, Kenny T, Kojima H, Lee K, Prieto P, Smith P, Smedley J, Stokes WS, Wnorowski G, Horgan G. Sewell F, et al. Among authors: holmes t. Regul Toxicol Pharmacol. 2015 Dec;73(3):770-9. doi: 10.1016/j.yrtph.2015.10.018. Epub 2015 Oct 23. Regul Toxicol Pharmacol. 2015. PMID: 26505531 Free article.
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals.
Luijten M, Corvi R, Mehta J, Corvaro M, Delrue N, Felter S, Haas B, Hewitt NJ, Hilton G, Holmes T, Jacobs MN, Jacobs A, Lamplmair F, Lewis D, Madia F, Manou I, Melching-Kollmuss S, Schorsch F, Schütte K, Sewell F, Strupp C, van der Laan JW, Wolf DC, Wolterink G, Woutersen R, Zvonar Z, Heusinkveld H, Braakhuis H. Luijten M, et al. Among authors: holmes t. Regul Toxicol Pharmacol. 2020 Dec;118:104789. doi: 10.1016/j.yrtph.2020.104789. Epub 2020 Oct 7. Regul Toxicol Pharmacol. 2020. PMID: 33035627 Free article. Review.
Regional particle size dependent deposition of inhaled aerosols in rats and mice.
Kuehl PJ, Anderson TL, Candelaria G, Gershman B, Harlin K, Hesterman JY, Holmes T, Hoppin J, Lackas C, Norenberg JP, Yu H, McDonald JD. Kuehl PJ, et al. Among authors: holmes t. Inhal Toxicol. 2012 Jan;24(1):27-35. doi: 10.3109/08958378.2011.632787. Epub 2011 Dec 7. Inhal Toxicol. 2012. PMID: 22145784
Lung deposition of droplet aerosols in monkeys.
Cheng YS, Irshad H, Kuehl P, Holmes TD, Sherwood R, Hobbs CH. Cheng YS, et al. Among authors: holmes td. Inhal Toxicol. 2008 Sep;20(11):1029-36. doi: 10.1080/08958370802105413. Inhal Toxicol. 2008. PMID: 18720170
950 results