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Conditional Deletion of Hsd11b2 in the Brain Causes Salt Appetite and Hypertension.
Evans LC, Ivy JR, Wyrwoll C, McNairn JA, Menzies RI, Christensen TH, Al-Dujaili EA, Kenyon CJ, Mullins JJ, Seckl JR, Holmes MC, Bailey MA. Evans LC, et al. Among authors: holmes mc. Circulation. 2016 Apr 5;133(14):1360-70. doi: 10.1161/CIRCULATIONAHA.115.019341. Epub 2016 Mar 7. Circulation. 2016. PMID: 26951843 Free PMC article.
Corticosteroid Receptors in Cardiac Health and Disease.
Ivy JR, Gray GA, Holmes MC, Denvir MA, Chapman KE. Ivy JR, et al. Among authors: holmes mc. Adv Exp Med Biol. 2022;1390:109-122. doi: 10.1007/978-3-031-11836-4_6. Adv Exp Med Biol. 2022. PMID: 36107315
Fetal brain 11β-hydroxysteroid dehydrogenase type 2 selectively determines programming of adult depressive-like behaviors and cognitive function, but not anxiety behaviors in male mice.
Wyrwoll C, Keith M, Noble J, Stevenson PL, Bombail V, Crombie S, Evans LC, Bailey MA, Wood E, Seckl JR, Holmes MC. Wyrwoll C, et al. Among authors: holmes mc. Psychoneuroendocrinology. 2015 Sep;59:59-70. doi: 10.1016/j.psyneuen.2015.05.003. Epub 2015 May 18. Psychoneuroendocrinology. 2015. PMID: 26036451 Free PMC article.
Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet.
Michailidou Z, Carter RN, Marshall E, Sutherland HG, Brownstein DG, Owen E, Cockett K, Kelly V, Ramage L, Al-Dujaili EA, Ross M, Maraki I, Newton K, Holmes MC, Seckl JR, Morton NM, Kenyon CJ, Chapman KE. Michailidou Z, et al. Among authors: holmes mc. FASEB J. 2008 Nov;22(11):3896-907. doi: 10.1096/fj.08-111914. Epub 2008 Aug 12. FASEB J. 2008. PMID: 18697839 Free PMC article.
229 results