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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice.
Mock ED, Mustafa M, Gunduz-Cinar O, Cinar R, Petrie GN, Kantae V, Di X, Ogasawara D, Varga ZV, Paloczi J, Miliano C, Donvito G, van Esbroeck ACM, van der Gracht AMF, Kotsogianni I, Park JK, Martella A, van der Wel T, Soethoudt M, Jiang M, Wendel TJ, Janssen APA, Bakker AT, Donovan CM, Castillo LI, Florea BI, Wat J, van den Hurk H, Wittwer M, Grether U, Holmes A, van Boeckel CAA, Hankemeier T, Cravatt BF, Buczynski MW, Hill MN, Pacher P, Lichtman AH, van der Stelt M. Mock ED, et al. Among authors: holmes a. Nat Chem Biol. 2020 Jun;16(6):667-675. doi: 10.1038/s41589-020-0528-7. Epub 2020 May 11. Nat Chem Biol. 2020. PMID: 32393901 Free PMC article.
Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity.
Gunduz-Cinar O, MacPherson KP, Cinar R, Gamble-George J, Sugden K, Williams B, Godlewski G, Ramikie TS, Gorka AX, Alapafuja SO, Nikas SP, Makriyannis A, Poulton R, Patel S, Hariri AR, Caspi A, Moffitt TE, Kunos G, Holmes A. Gunduz-Cinar O, et al. Among authors: holmes a. Mol Psychiatry. 2013 Jul;18(7):813-23. doi: 10.1038/mp.2012.72. Epub 2012 Jun 12. Mol Psychiatry. 2013. PMID: 22688188 Free PMC article.
GluN2B in corticostriatal circuits governs choice learning and choice shifting.
Brigman JL, Daut RA, Wright T, Gunduz-Cinar O, Graybeal C, Davis MI, Jiang Z, Saksida LM, Jinde S, Pease M, Bussey TJ, Lovinger DM, Nakazawa K, Holmes A. Brigman JL, et al. Among authors: holmes a. Nat Neurosci. 2013 Aug;16(8):1101-10. doi: 10.1038/nn.3457. Epub 2013 Jul 7. Nat Neurosci. 2013. PMID: 23831965 Free PMC article.
Chronic alcohol produces neuroadaptations to prime dorsal striatal learning.
DePoy L, Daut R, Brigman JL, MacPherson K, Crowley N, Gunduz-Cinar O, Pickens CL, Cinar R, Saksida LM, Kunos G, Lovinger DM, Bussey TJ, Camp MC, Holmes A. DePoy L, et al. Among authors: holmes a. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14783-8. doi: 10.1073/pnas.1308198110. Epub 2013 Aug 19. Proc Natl Acad Sci U S A. 2013. PMID: 23959891 Free PMC article.
Prefrontal single-unit firing associated with deficient extinction in mice.
Fitzgerald PJ, Whittle N, Flynn SM, Graybeal C, Pinard CR, Gunduz-Cinar O, Kravitz AV, Singewald N, Holmes A. Fitzgerald PJ, et al. Among authors: holmes a. Neurobiol Learn Mem. 2014 Sep;113:69-81. doi: 10.1016/j.nlm.2013.11.002. Epub 2013 Nov 11. Neurobiol Learn Mem. 2014. PMID: 24231425 Free PMC article.
2,591 results