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Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in mortality.
Sabharwal A, Wishman MD, Cervera RL, Serres MR, Anderson JL, Holmberg SR, Kar B, Treichel AJ, Ichino N, Liu W, Yang J, Ding Y, Deng Y, Lacey JM, Laxen WJ, Loken PR, Oglesbee D, Farber SA, Clark KJ, Xu X, Ekker SC. Sabharwal A, et al. Among authors: holmberg sr. Elife. 2022 Nov 21;11:e65488. doi: 10.7554/eLife.65488. Elife. 2022. PMID: 36408801 Free PMC article.
The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells In Vitro and Zebrafish Disease Models In Vivo.
Sabharwal A, Kar B, Restrepo-Castillo S, Holmberg SR, Mathew ND, Kendall BL, Cotter RP, WareJoncas Z, Seiler C, Nakamaru-Ogiso E, Clark KJ, Ekker SC. Sabharwal A, et al. Among authors: holmberg sr. CRISPR J. 2021 Dec;4(6):799-821. doi: 10.1089/crispr.2021.0061. Epub 2021 Nov 30. CRISPR J. 2021. PMID: 34847747 Free PMC article.
A Primer Genetic Toolkit for Exploring Mitochondrial Biology and Disease Using Zebrafish.
Sabharwal A, Campbell JM, Schwab TL, WareJoncas Z, Wishman MD, Ata H, Liu W, Ichino N, Hunter DE, Bergren JD, Urban MD, Urban RM, Holmberg SR, Kar B, Cook A, Ding Y, Xu X, Clark KJ, Ekker SC. Sabharwal A, et al. Among authors: holmberg sr. Genes (Basel). 2022 Jul 23;13(8):1317. doi: 10.3390/genes13081317. Genes (Basel). 2022. PMID: 35893052 Free PMC article.
18 results