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The novel cytotoxic polybisphosphonate osteodex decreases bone resorption by enhancing cell death of mature osteoclasts without affecting osteoclastogenesis of RANKL-stimulated mouse bone marrow macrophages.
Henning P, Westerlund A, Movérare-Skrtic S, Lindholm C, Márquez-Méndez M, Nilsson S, Holmberg AR, Lerner UH. Henning P, et al. Among authors: holmberg ar. Invest New Drugs. 2024 Apr;42(2):207-220. doi: 10.1007/s10637-024-01427-1. Epub 2024 Mar 1. Invest New Drugs. 2024. PMID: 38427117 Free PMC article.
Mediation of Age and Thrombectomy Outcome by Neuroimaging Markers of Frailty in Patients With Stroke.
Benali F, Singh N, Fladt J, Jaroenngarmsamer T, Bala F, Ospel JM, Buck BH, Dowlatshahi D, Field TS, Hanel RA, Peeling L, Tymianski M, Hill MD, Goyal M, Ganesh A; ESCAPE-NA1 Investigators. Benali F, et al. JAMA Netw Open. 2024 Jan 2;7(1):e2349628. doi: 10.1001/jamanetworkopen.2023.49628. JAMA Netw Open. 2024. PMID: 38165676 Free PMC article. Clinical Trial.
Cytotoxicity of poly-guanidine in medulloblastoma cell lines.
Gallo-Oller G, de Ståhl TD, Alaiya A, Nilsson S, Holmberg AR, Márquez-Méndez M. Gallo-Oller G, et al. Among authors: holmberg ar. Invest New Drugs. 2023 Oct;41(5):688-698. doi: 10.1007/s10637-023-01386-z. Epub 2023 Aug 9. Invest New Drugs. 2023. PMID: 37556022 Free PMC article.
Dual-Layer Detector Cone-Beam CT Angiography for Stroke Assessment: First-in-Human Results (the Next Generation X-ray Imaging System Trial).
Ståhl F, Almqvist H, Kolloch J, Aspelin Å, Gontu V, Hummel E, van Vlimmeren M, Simon M, Thran A, Holmberg Å, Mazya MV, Söderman M, Delgado AF. Ståhl F, et al. Among authors: holmberg a. AJNR Am J Neuroradiol. 2023 May;44(5):523-529. doi: 10.3174/ajnr.A7835. Epub 2023 Apr 13. AJNR Am J Neuroradiol. 2023. PMID: 37055159 Free PMC article.
A randomised, double-blind, dose-finding, phase II multicentre study of ODX in the treatment of patients with castration-resistant prostate cancer and skeletal metastases.
Thellenberg-Karlsson C, Vjaters E, Kase M, Tammela T, Ojamaa K, Norming U, Nyman C, Andersson SO, Hublarovs O, Marquez-Holmberg M, Castellanos E, Ullen A, Holmberg A, Nilsson S. Thellenberg-Karlsson C, et al. Among authors: holmberg a. Eur J Cancer. 2023 Mar;181:198-207. doi: 10.1016/j.ejca.2022.12.006. Epub 2022 Dec 20. Eur J Cancer. 2023. PMID: 36682096 Free article. Clinical Trial.
Characterization of Selective and Potent JAK1 Inhibitors Intended for the Inhaled Treatment of Asthma.
Nilsson M, Rhedin M, Hendrickx R, Berglund S, Piras A, Blomgran P, Cavallin A, Collins M, Dahl G, Dekkak B, Ericsson T, Hagberg N, Holmberg AA, Leffler A, Lundqvist AJ, Markou T, Pinkerton J, Rönnblom L, Siu S, Taylor V, Wennberg T, Zervas D, Laurence ADJ, Mitra S, Belvisi MG, Birrell M, Borde A. Nilsson M, et al. Among authors: holmberg aa. Drug Des Devel Ther. 2022 Aug 31;16:2901-2917. doi: 10.2147/DDDT.S354291. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 36068788 Free PMC article.
209 results