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A Brain-Permeable Aminosterol Regulates Cell Membranes to Mitigate the Toxicity of Diverse Pore-Forming Agents.
Kreiser RP, Wright AK, Sasser LR, Rinauro DJ, Gabriel JM, Hsu CM, Hurtado JA, McKenzie TL, Errico S, Albright JA, Richardson L, Jaffett VA, Riegner DE, Nguyen LT, LeForte K, Zasloff M, Hollows JE, Chiti F, Vendruscolo M, Limbocker R. Kreiser RP, et al. Among authors: hollows je. ACS Chem Neurosci. 2022 Apr 20;13(8):1219-1231. doi: 10.1021/acschemneuro.1c00840. Epub 2022 Apr 11. ACS Chem Neurosci. 2022. PMID: 35404569 Free PMC article.
Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers.
Limbocker R, Staats R, Chia S, Ruggeri FS, Mannini B, Xu CK, Perni M, Cascella R, Bigi A, Sasser LR, Block NR, Wright AK, Kreiser RP, Custy ET, Meisl G, Errico S, Habchi J, Flagmeier P, Kartanas T, Hollows JE, Nguyen LT, LeForte K, Barbut D, Kumita JR, Cecchi C, Zasloff M, Knowles TPJ, Dobson CM, Chiti F, Vendruscolo M. Limbocker R, et al. Among authors: hollows je. Front Neurosci. 2021 Jun 18;15:680026. doi: 10.3389/fnins.2021.680026. eCollection 2021. Front Neurosci. 2021. PMID: 34220435 Free PMC article.
Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers.
Kreiser RP, Wright AK, Block NR, Hollows JE, Nguyen LT, LeForte K, Mannini B, Vendruscolo M, Limbocker R. Kreiser RP, et al. Among authors: hollows je. Int J Mol Sci. 2020 Nov 17;21(22):8651. doi: 10.3390/ijms21228651. Int J Mol Sci. 2020. PMID: 33212787 Free PMC article. Review.