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Molecular breeding of polymerases for amplification of ancient DNA.
d'Abbadie M, Hofreiter M, Vaisman A, Loakes D, Gasparutto D, Cadet J, Woodgate R, Pääbo S, Holliger P. d'Abbadie M, et al. Among authors: holliger p. Nat Biotechnol. 2007 Aug;25(8):939-43. doi: 10.1038/nbt1321. Epub 2007 Jul 15. Nat Biotechnol. 2007. PMID: 17632524 Free PMC article.
Evolving a polymerase for hydrophobic base analogues.
Loakes D, Gallego J, Pinheiro VB, Kool ET, Holliger P. Loakes D, et al. Among authors: holliger p. J Am Chem Soc. 2009 Oct 21;131(41):14827-37. doi: 10.1021/ja9039696. J Am Chem Soc. 2009. PMID: 19778048 Free PMC article.
A short adaptive path from DNA to RNA polymerases.
Cozens C, Pinheiro VB, Vaisman A, Woodgate R, Holliger P. Cozens C, et al. Among authors: holliger p. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8067-72. doi: 10.1073/pnas.1120964109. Epub 2012 May 7. Proc Natl Acad Sci U S A. 2012. PMID: 22566643 Free PMC article.
A polymerase engineered for bisulfite sequencing.
Millar D, Christova Y, Holliger P. Millar D, et al. Among authors: holliger p. Nucleic Acids Res. 2015 Dec 15;43(22):e155. doi: 10.1093/nar/gkv798. Epub 2015 Aug 13. Nucleic Acids Res. 2015. PMID: 26271989 Free PMC article.
92 results