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The Kinase IKKβ Regulates a STING-and NF-κB-Dependent Antiviral Response Pathway in Drosophila.
Goto A, Okado K, Martins N, Cai H, Barbier V, Lamiable O, Troxler L, Santiago E, Kuhn L, Paik D, Silverman N, Holleufer A, Hartmann R, Liu J, Peng T, Hoffmann JA, Meignin C, Daeffler L, Imler JL. Goto A, et al. Among authors: holleufer a. Immunity. 2020 Jan 14;52(1):200. doi: 10.1016/j.immuni.2019.12.009. Immunity. 2020. PMID: 31940269 Free article. No abstract available.
The Kinase IKKβ Regulates a STING- and NF-κB-Dependent Antiviral Response Pathway in Drosophila.
Goto A, Okado K, Martins N, Cai H, Barbier V, Lamiable O, Troxler L, Santiago E, Kuhn L, Paik D, Silverman N, Holleufer A, Hartmann R, Liu J, Peng T, Hoffmann JA, Meignin C, Daeffler L, Imler JL. Goto A, et al. Among authors: holleufer a. Immunity. 2018 Aug 21;49(2):225-234.e4. doi: 10.1016/j.immuni.2018.07.013. Epub 2018 Aug 14. Immunity. 2018. PMID: 30119996 Free PMC article.
Length dependent activation of OAS proteins by dsRNA.
Wang Y, Holleufer A, Gad HH, Hartmann R. Wang Y, et al. Among authors: holleufer a. Cytokine. 2020 Feb;126:154867. doi: 10.1016/j.cyto.2019.154867. Epub 2019 Oct 17. Cytokine. 2020. PMID: 31629990
Two cGAS-like receptors induce antiviral immunity in Drosophila.
Holleufer A, Winther KG, Gad HH, Ai X, Chen Y, Li L, Wei Z, Deng H, Liu J, Frederiksen NA, Simonsen B, Andersen LL, Kleigrewe K, Dalskov L, Pichlmair A, Cai H, Imler JL, Hartmann R. Holleufer A, et al. Nature. 2021 Sep;597(7874):114-118. doi: 10.1038/s41586-021-03800-z. Epub 2021 Jul 14. Nature. 2021. PMID: 34261128
cGAS is activated by DNA in a length-dependent manner.
Luecke S, Holleufer A, Christensen MH, Jønsson KL, Boni GA, Sørensen LK, Johannsen M, Jakobsen MR, Hartmann R, Paludan SR. Luecke S, et al. Among authors: holleufer a. EMBO Rep. 2017 Oct;18(10):1707-1715. doi: 10.15252/embr.201744017. Epub 2017 Aug 10. EMBO Rep. 2017. PMID: 28801534 Free PMC article.
SARS-CoV-2 elicits robust adaptive immune responses regardless of disease severity.
Nielsen SS, Vibholm LK, Monrad I, Olesen R, Frattari GS, Pahus MH, Højen JF, Gunst JD, Erikstrup C, Holleufer A, Hartmann R, Østergaard L, Søgaard OS, Schleimann MH, Tolstrup M. Nielsen SS, et al. Among authors: holleufer a. EBioMedicine. 2021 Jun;68:103410. doi: 10.1016/j.ebiom.2021.103410. Epub 2021 Jun 4. EBioMedicine. 2021. PMID: 34098342 Free PMC article.