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Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging.
Bogeska R, Mikecin AM, Kaschutnig P, Fawaz M, Büchler-Schäff M, Le D, Ganuza M, Vollmer A, Paffenholz SV, Asada N, Rodriguez-Correa E, Frauhammer F, Buettner F, Ball M, Knoch J, Stäble S, Walter D, Petri A, Carreño-Gonzalez MJ, Wagner V, Brors B, Haas S, Lipka DB, Essers MAG, Weru V, Holland-Letz T, Mallm JP, Rippe K, Krämer S, Schlesner M, McKinney Freeman S, Florian MC, King KY, Frenette PS, Rieger MA, Milsom MD. Bogeska R, et al. Among authors: holland letz t. Cell Stem Cell. 2022 Aug 4;29(8):1273-1284.e8. doi: 10.1016/j.stem.2022.06.012. Epub 2022 Jul 19. Cell Stem Cell. 2022. PMID: 35858618 Free PMC article.
Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.
Walter D, Lier A, Geiselhart A, Thalheimer FB, Huntscha S, Sobotta MC, Moehrle B, Brocks D, Bayindir I, Kaschutnig P, Muedder K, Klein C, Jauch A, Schroeder T, Geiger H, Dick TP, Holland-Letz T, Schmezer P, Lane SW, Rieger MA, Essers MA, Williams DA, Trumpp A, Milsom MD. Walter D, et al. Nature. 2015 Apr 23;520(7548):549-52. doi: 10.1038/nature14131. Epub 2015 Feb 18. Nature. 2015. PMID: 25707806
Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output.
Rommel MGE, Walz L, Fotopoulou F, Kohlscheen S, Schenk F, Miskey C, Botezatu L, Krebs Y, Voelker IM, Wittwer K, Holland-Letz T, Ivics Z, von Messling V, Essers MAG, Milsom MD, Pfaller CK, Modlich U. Rommel MGE, et al. Among authors: holland letz t. Cell Rep. 2022 Oct 4;41(1):111447. doi: 10.1016/j.celrep.2022.111447. Cell Rep. 2022. PMID: 36198277 Free article.
Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs.
Wünsche P, Eckert ESP, Holland-Letz T, Paruzynski A, Hotz-Wagenblatt A, Fronza R, Rath T, Gil-Farina I, Schmidt M, von Kalle C, Klein C, Ball CR, Herbst F, Glimm H. Wünsche P, et al. Cell Stem Cell. 2018 Jul 5;23(1):132-146.e9. doi: 10.1016/j.stem.2018.06.003. Cell Stem Cell. 2018. PMID: 29979988 Free article.
Biosensor for deconvolution of individual cell fate in response to ion beam irradiation.
Niklas M, Schlegel J, Liew H, Zimmermann F, Rein K, Walsh DWM, Dzyubachyk O, Holland-Letz T, Rahmanian S, Greilich S, Runz A, Jäkel O, Debus J, Abdollahi A. Niklas M, et al. Among authors: holland letz t. Cell Rep Methods. 2022 Feb 17;2(2):100169. doi: 10.1016/j.crmeth.2022.100169. eCollection 2022 Feb 28. Cell Rep Methods. 2022. PMID: 35474967 Free PMC article.
Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay.
Baccelli I, Schneeweiss A, Riethdorf S, Stenzinger A, Schillert A, Vogel V, Klein C, Saini M, Bäuerle T, Wallwiener M, Holland-Letz T, Höfner T, Sprick M, Scharpff M, Marmé F, Sinn HP, Pantel K, Weichert W, Trumpp A. Baccelli I, et al. Nat Biotechnol. 2013 Jun;31(6):539-44. doi: 10.1038/nbt.2576. Epub 2013 Apr 21. Nat Biotechnol. 2013. PMID: 23609047
miR-339-3p Is a Tumor Suppressor in Melanoma.
Weber CE, Luo C, Hotz-Wagenblatt A, Gardyan A, Kordaß T, Holland-Letz T, Osen W, Eichmüller SB. Weber CE, et al. Cancer Res. 2016 Jun 15;76(12):3562-71. doi: 10.1158/0008-5472.CAN-15-2932. Epub 2016 Apr 15. Cancer Res. 2016. PMID: 27197185
116 results