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The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure.
Cluntun AA, Badolia R, Lettlova S, Parnell KM, Shankar TS, Diakos NA, Olson KA, Taleb I, Tatum SM, Berg JA, Cunningham CN, Van Ry T, Bott AJ, Krokidi AT, Fogarty S, Skedros S, Swiatek WI, Yu X, Luo B, Merx S, Navankasattusas S, Cox JE, Ducker GS, Holland WL, McKellar SH, Rutter J, Drakos SG. Cluntun AA, et al. Among authors: holland wl. Cell Metab. 2021 Mar 2;33(3):629-648.e10. doi: 10.1016/j.cmet.2020.12.003. Epub 2020 Dec 16. Cell Metab. 2021. PMID: 33333007 Free PMC article.
Phospholipid methylation regulates muscle metabolic rate through Ca2+ transport efficiency.
Verkerke ARP, Ferrara PJ, Lin CT, Johnson JM, Ryan TE, Maschek JA, Eshima H, Paran CW, Laing BT, Siripoksup P, Tippetts TS, Wentzler EJ, Huang H, Spangenburg EE, Brault JJ, Villanueva CJ, Summers SA, Holland WL, Cox JE, Vance DE, Neufer PD, Funai K. Verkerke ARP, et al. Among authors: holland wl. Nat Metab. 2019 Sep;1(9):876-885. doi: 10.1038/s42255-019-0111-2. Epub 2019 Sep 16. Nat Metab. 2019. PMID: 32405618 Free PMC article.
Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis.
Panic V, Pearson S, Banks J, Tippetts TS, Velasco-Silva JN, Lee S, Simcox J, Geoghegan G, Bensard CL, van Ry T, Holland WL, Summers SA, Cox J, Ducker GS, Rutter J, Villanueva CJ. Panic V, et al. Among authors: holland wl. Elife. 2020 Aug 14;9:e52558. doi: 10.7554/eLife.52558. Elife. 2020. PMID: 32795388 Free PMC article.
Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle.
Ferrara PJ, Rong X, Maschek JA, Verkerke AR, Siripoksup P, Song H, Green TD, Krishnan KC, Johnson JM, Turk J, Houmard JA, Lusis AJ, Drummond MJ, McClung JM, Cox JE, Shaikh SR, Tontonoz P, Holland WL, Funai K. Ferrara PJ, et al. Among authors: holland wl. J Clin Invest. 2021 Apr 15;131(8):e135963. doi: 10.1172/JCI135963. J Clin Invest. 2021. PMID: 33591957 Free PMC article.
Ceramides and other sphingolipids as drivers of cardiovascular disease.
Choi RH, Tatum SM, Symons JD, Summers SA, Holland WL. Choi RH, et al. Among authors: holland wl. Nat Rev Cardiol. 2021 Oct;18(10):701-711. doi: 10.1038/s41569-021-00536-1. Epub 2021 Mar 26. Nat Rev Cardiol. 2021. PMID: 33772258 Free PMC article. Review.
Integrating molecular and clinical variables to predict myocardial recovery.
Visker JR, Brintz BJ, Kyriakopoulos CP, Hillas Y, Taleb I, Badolia R, Shankar TS, Amrute JM, Ling J, Hamouche R, Tseliou E, Navankasattusas S, Wever-Pinzon O, Ducker GS, Holland WL, Summers SA, Koenig SC, Hanff TC, Lavine KJ, Murali S, Bailey S, Alharethi R, Selzman CH, Shah P, Slaughter MS, Kanwar MK, Drakos SG. Visker JR, et al. Among authors: holland wl. bioRxiv [Preprint]. 2024 Apr 20:2024.04.16.589326. doi: 10.1101/2024.04.16.589326. bioRxiv. 2024. PMID: 38659908 Free PMC article. Preprint.
126 results