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Rational library design by functional CDR resampling.
Zhao Q, Buhr D, Gunter C, Frenette J, Ferguson M, Sanford E, Holland E, Rajagopal C, Batonick M, Kiss MM, Weiner MP. Zhao Q, et al. Among authors: holland e. N Biotechnol. 2018 Oct 25;45:89-97. doi: 10.1016/j.nbt.2017.12.005. Epub 2017 Dec 11. N Biotechnol. 2018. PMID: 29242049 Free PMC article.
All-trans retinoic acid induces durable tumor immunity in IDH-mutant gliomas by rescuing transcriptional repression of the CRBP1-retinoic acid axis.
Rao A, Zhang X, Cillo AR, Sussman JH, Sandlesh P, Tarbay AC, Mallela AN, Cardello C, Krueger K, Xu J, Li A, Xu J, Patterson J, Akca E, Angione A, Jaman E, Kim WJ, Allen J, Venketeswaran A, Zinn PO, Parise R, Beumer J, Duensing A, Holland EC, Ferris R, Bagley SJ, Bruno TC, Vignali DAA, Agnihotri S, Amankulor NM. Rao A, et al. Among authors: holland ec. bioRxiv [Preprint]. 2024 Apr 13:2024.04.09.588752. doi: 10.1101/2024.04.09.588752. bioRxiv. 2024. PMID: 38645178 Free PMC article. Preprint.
Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype.
Nuechterlein N, Shelbourn A, Szulzewsky F, Arora S, Casad M, Pattwell S, Merino-Galan L, Sulman E, Arowa S, Alvinez N, Jung M, Brown D, Tang K, Jackson S, Stoica S, Chittaboina P, Banasavadi-Siddegowda YK, Wirsching HG, Stella N, Shapiro L, Paddison P, Patel AP, Gilbert MR, Abdullaev Z, Aldape K, Pratt D, Holland EC, Cimino PJ. Nuechterlein N, et al. Among authors: holland ec. Genes Dev. 2024 Apr 17;38(5-6):273-288. doi: 10.1101/gad.351350.123. Genes Dev. 2024. PMID: 38589034
872 results