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Trial of Prasinezumab in Early-Stage Parkinson's Disease.
Pagano G, Taylor KI, Anzures-Cabrera J, Marchesi M, Simuni T, Marek K, Postuma RB, Pavese N, Stocchi F, Azulay JP, Mollenhauer B, López-Manzanares L, Russell DS, Boyd JT, Nicholas AP, Luquin MR, Hauser RA, Gasser T, Poewe W, Ricci B, Boulay A, Vogt A, Boess FG, Dukart J, D'Urso G, Finch R, Zanigni S, Monnet A, Pross N, Hahn A, Svoboda H, Britschgi M, Lipsmeier F, Volkova-Volkmar E, Lindemann M, Dziadek S, Holiga Š, Rukina D, Kustermann T, Kerchner GA, Fontoura P, Umbricht D, Doody R, Nikolcheva T, Bonni A; PASADENA Investigators; Prasinezumab Study Group. Pagano G, et al. Among authors: holiga s. N Engl J Med. 2022 Aug 4;387(5):421-432. doi: 10.1056/NEJMoa2202867. N Engl J Med. 2022. PMID: 35921451 Clinical Trial.
A Phase II Study to Evaluate the Safety and Efficacy of Prasinezumab in Early Parkinson's Disease (PASADENA): Rationale, Design, and Baseline Data.
Pagano G, Boess FG, Taylor KI, Ricci B, Mollenhauer B, Poewe W, Boulay A, Anzures-Cabrera J, Vogt A, Marchesi M, Post A, Nikolcheva T, Kinney GG, Zago WM, Ness DK, Svoboda H, Britschgi M, Ostrowitzki S, Simuni T, Marek K, Koller M, Sevigny J, Doody R, Fontoura P, Umbricht D, Bonni A; PASADENA Investigators; Prasinezumab Study Group. Pagano G, et al. Front Neurol. 2021 Oct 1;12:705407. doi: 10.3389/fneur.2021.705407. eCollection 2021. Front Neurol. 2021. PMID: 34659081 Free PMC article.
Proof-of-Mechanism Study of the Phosphodiesterase 10 Inhibitor RG7203 in Patients With Schizophrenia and Negative Symptoms.
Umbricht D, Abt M, Tamburri P, Chatham C, Holiga Š, Frank MJ, Collins AGE, Walling DP, Mofsen R, Gruener D, Gertsik L, Sevigny J, Keswani S, Dukart J. Umbricht D, et al. Among authors: holiga s. Biol Psychiatry Glob Open Sci. 2021 Mar 13;1(1):70-77. doi: 10.1016/j.bpsgos.2021.03.001. eCollection 2021 Jun. Biol Psychiatry Glob Open Sci. 2021. PMID: 36324430 Free PMC article.
Cerebral blood flow predicts differential neurotransmitter activity.
Dukart J, Holiga Š, Chatham C, Hawkins P, Forsyth A, McMillan R, Myers J, Lingford-Hughes AR, Nutt DJ, Merlo-Pich E, Risterucci C, Boak L, Umbricht D, Schobel S, Liu T, Mehta MA, Zelaya FO, Williams SC, Brown G, Paulus M, Honey GD, Muthukumaraswamy S, Hipp J, Bertolino A, Sambataro F. Dukart J, et al. Among authors: holiga s. Sci Rep. 2018 Mar 6;8(1):4074. doi: 10.1038/s41598-018-22444-0. Sci Rep. 2018. PMID: 29511260 Free PMC article.
Brain connectivity changes when comparing effects of subthalamic deep brain stimulation with levodopa treatment in Parkinson's disease.
Mueller K, Jech R, Růžička F, Holiga Š, Ballarini T, Bezdicek O, Möller HE, Vymazal J, Růžička E, Schroeter ML, Urgošík D. Mueller K, et al. Among authors: holiga s. Neuroimage Clin. 2018 May 9;19:1025-1035. doi: 10.1016/j.nicl.2018.05.006. eCollection 2018. Neuroimage Clin. 2018. PMID: 30035027 Free PMC article.
27 results