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Metabolic activation of tachysterol3 to biologically active hydroxyderivatives that act on VDR, AhR, LXRs, and PPARγ receptors.
Slominski AT, Kim TK, Slominski RM, Song Y, Janjetovic Z, Podgorska E, Reddy SB, Song Y, Raman C, Tang EKY, Fabisiak A, Brzeminski P, Sicinski RR, Atigadda V, Jetten AM, Holick MF, Tuckey RC. Slominski AT, et al. Among authors: holick mf. FASEB J. 2022 Aug;36(8):e22451. doi: 10.1096/fj.202200578R. FASEB J. 2022. PMID: 35838947 Free PMC article.
Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.
Slominski AT, Janjetovic Z, Fuller BE, Zmijewski MA, Tuckey RC, Nguyen MN, Sweatman T, Li W, Zjawiony J, Miller D, Chen TC, Lozanski G, Holick MF. Slominski AT, et al. Among authors: holick mf. PLoS One. 2010 Mar 26;5(3):e9907. doi: 10.1371/journal.pone.0009907. PLoS One. 2010. PMID: 20360850 Free PMC article.
20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells.
Slominski AT, Kim TK, Janjetovic Z, Tuckey RC, Bieniek R, Yue J, Li W, Chen J, Nguyen MN, Tang EK, Miller D, Chen TC, Holick M. Slominski AT, et al. Am J Physiol Cell Physiol. 2011 Mar;300(3):C526-41. doi: 10.1152/ajpcell.00203.2010. Epub 2010 Dec 15. Am J Physiol Cell Physiol. 2011. PMID: 21160030 Free PMC article.
Protective effects of novel derivatives of vitamin D3 and lumisterol against UVB-induced damage in human keratinocytes involve activation of Nrf2 and p53 defense mechanisms.
Chaiprasongsuk A, Janjetovic Z, Kim TK, Jarrett SG, D'Orazio JA, Holick MF, Tang EKY, Tuckey RC, Panich U, Li W, Slominski AT. Chaiprasongsuk A, et al. Among authors: holick mf. Redox Biol. 2019 Jun;24:101206. doi: 10.1016/j.redox.2019.101206. Epub 2019 Apr 20. Redox Biol. 2019. PMID: 31039479 Free PMC article.
Photoprotective Properties of Vitamin D and Lumisterol Hydroxyderivatives.
Slominski AT, Chaiprasongsuk A, Janjetovic Z, Kim TK, Stefan J, Slominski RM, Hanumanthu VS, Raman C, Qayyum S, Song Y, Song Y, Panich U, Crossman DK, Athar M, Holick MF, Jetten AM, Zmijewski MA, Zmijewski J, Tuckey RC. Slominski AT, et al. Among authors: holick mf. Cell Biochem Biophys. 2020 Jun;78(2):165-180. doi: 10.1007/s12013-020-00913-6. Epub 2020 May 22. Cell Biochem Biophys. 2020. PMID: 32441029 Free PMC article. Review.
COVID-19 and Vitamin D: A lesson from the skin.
Slominski RM, Stefan J, Athar M, Holick MF, Jetten AM, Raman C, Slominski AT. Slominski RM, et al. Among authors: holick mf. Exp Dermatol. 2020 Sep;29(9):885-890. doi: 10.1111/exd.14170. Epub 2020 Sep 9. Exp Dermatol. 2020. PMID: 32779213 Free PMC article.
606 results