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Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures.
Schoof M, Godbole S, Albert TK, Dottermusch M, Walter C, Ballast A, Qin N, Olivera MB, Göbel C, Neyazi S, Holdhof D, Kresbach C, Peter LS, Epplen GD, Thaden V, Spohn M, Blattner-Johnson M, Modemann F, Mynarek M, Rutkowski S, Sill M, Varghese J, Afflerbach AK, Eckhardt A, Münter D, Verma A, Struve N, Jones DTW, Remke M, Neumann JE, Kerl K, Schüller U. Schoof M, et al. Among authors: holdhof d. Nat Commun. 2023 Nov 24;14(1):7717. doi: 10.1038/s41467-023-43564-w. Nat Commun. 2023. PMID: 38001143 Free PMC article.
Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors.
Graf M, Interlandi M, Moreno N, Holdhof D, Göbel C, Melcher V, Mertins J, Albert TK, Kastrati D, Alfert A, Holsten T, de Faria F, Meisterernst M, Rossig C, Warmuth-Metz M, Nowak J, Meyer Zu Hörste G, Mayère C, Nef S, Johann P, Frühwald MC, Dugas M, Schüller U, Kerl K. Graf M, et al. Among authors: holdhof d. Nat Commun. 2022 Mar 22;13(1):1544. doi: 10.1038/s41467-022-29152-4. Nat Commun. 2022. PMID: 35318328 Free PMC article.
The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration.
Schoof M, Launspach M, Holdhof D, Nguyen L, Engel V, Filser S, Peters F, Immenschuh J, Hellwig M, Niesen J, Mall V, Ertl-Wagner B, Hagel C, Spohn M, Lutz B, Sedlacik J, Indenbirken D, Merk DJ, Schüller U. Schoof M, et al. Among authors: holdhof d. Acta Neuropathol Commun. 2019 Dec 5;7(1):199. doi: 10.1186/s40478-019-0849-5. Acta Neuropathol Commun. 2019. PMID: 31806049 Free PMC article.
A Carboxy-terminal Smarcb1 Point Mutation Induces Hydrocephalus Formation and Affects AP-1 and Neuronal Signalling Pathways in Mice.
Brugmans AK, Walter C, Moreno N, Göbel C, Holdhof D, de Faria FW, Hotfilder M, Jeising D, Frühwald MC, Skryabin BV, Rozhdestvensky TS, Wachsmuth L, Faber C, Dugas M, Varghese J, Schüller U, Albert TK, Kerl K. Brugmans AK, et al. Among authors: holdhof d. Cell Mol Neurobiol. 2023 Oct;43(7):3511-3526. doi: 10.1007/s10571-023-01361-5. Epub 2023 May 23. Cell Mol Neurobiol. 2023. PMID: 37219662 Free PMC article.
20 results